Nadia A Abdelkader1, Waheed Abd El Monsef1, Ahmed F Helal1, Ghada A Ismail2, Dalia H Abdelhamid2, Maha M El Gaafary3, Khaled Raafat4, Yasser A Abd El Razek1 and Ahmed Fouad Sherief1*
1Tropical Medicine Department, Ain Shams University, Cairo, Egypt
2Clinical Pathology Department, Ain Shams University, Cairo, Egypt
3Public Health and Community Medicine, Ain Shams University, Cairo, Egypt
4Internal Medicine, Gastroenterology and Hepatology, Ain Shams University, Cairo, Egypt
*Corresponding Author: Ahmed Fouad Sherief, Tropical Medicine Department, Faculty of Medicine, Ain Shams University, Abbasia, Cairo, Egypt.
Received: September 24, 2020; Published: October 22, 2020
Purpose: Assessment of Triggering Receptor Expressed on Myeloid Cells (TREM-1) levels in the diagnosis of SBP and effectiveness of treatment among Egyptian cirrhotic ascitic patients.
Methods: This was a Prospective case-control study, which was conducted on 60 cirrhotic ascitic patients, and divided into two groups:
Results: There was a high statistically significant difference between the two groups in the baseline level of TREM-1 while the mean was higher 1280 pg/ml (± 1136.9) with a level range between (580 - 4500 pg/ml) among patients with SBP Than the control group mean 129.9 pg/ml (± 51.9) with a level range between (60 - 250 pg/ml) among. Besides, it was found a statistically significant difference in the level of TREM-1 before and after treatment among patients with SBP. The mean of TREM-1 before treatment was higher 1280.6 pg/ml (± 1136.9) than a mean 376.2 pg/ml (± 78.4) and level range between (260 - 560 pg/ml) after the treatment.
Conclusion: TREM-1 is an easy, rapid, and reliable diagnostic tool for SPB which also harbors great value in following up patients with SBP.
Keywords: CLD; Ascites; Spontaneous Bacterial Peritonitis; Ascitic TREM-1 Level; Ascitic Culture
Citation: Ahmed Fouad Sherief., et al. "Spontaneous Bacterial Peritonitis in Cirrhotic Patients: Triggering Receptor Expressed on Myeloid Cells (TREM-1) as a Valid Marker". Acta Scientific Gastrointestinal Disorders 3.11 (2020): 23-27.
Copyright: © 2020 Ahmed Fouad Sherief., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.