Acta Scientific Gastrointestinal Disorders (ISSN: 2582-1091)

Case Report Volume 3 Issue 11

Dietary Therapy in Adult Inflammatory Bowel Disease. Is there a Role in 2020?

Gim Hin Ho1* and Ee Ling Yeong Hazel2

1Division of Gastroenterology, Department of General Medicine, Khoo Teck Puat Hospital, Singapore
2Department of Nutrition and Dietetics, Khoo Teck Puat Hospital, Singapore

*Corresponding Author: Gim Hin Ho, Division of Gastroenterology, Department of General Medicine, Khoo Teck Puat Hospital, Singapore.

Received: August 20, 2020; Published: September 16, 2020

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The exact pathogenesis of inflammatory bowel disease (IBD) remains uncertain but has been strongly postulated to be influenced by modifiable non-genetic environmental factors. One of these factors is the dysbiotic alteration in the gut microbiome [1]. As a result, research into the alteration of the microbiome by probiotics [2-5], faecal microbiota transplant [6] and diet as potential therapeutic strategies have gathered pace over the past few years. The principle of these interventions presumes that reconfiguration of the microbiome toward a more “eubiotic” or less proinflammatory profile would lead to a reduction of intestinal inflammation [1]. Diet has been hypothesized to play a role in the pathogenesis in inflammation, with research showing the effect of dietary exposures on the intestinal microbiome as well as mucosal integrity.

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References

  1. Limketkai BN., et al. “Diet Therapy for Inflammatory Bowel Disease: A Call to the Dining Table”. Inflammatory Bowel Disease 4 (2019): 510-514.
  2. Butterworth AD., et al. “Probiotics for induction of remission in Crohn’s disease”. Cochrane Database of Systematic Reviews 3 (2008): CD006634.
  3. Rolfe VE., et al. “Probiotics for maintenance of remission in Crohn’s disease”. Cochrane Database of Systematic Reviews 4 (2006): CD004826.
  4. Naidoo K., et al. “Probiotics for maintenance of remission in ulcerative colitis”. Cochrane Database of Systematic Reviews 12 (2011): CD007443.
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  9. Mowat C., et al. “IBD Section of the British Society of Gastroenterology. Guidelines for the management of inflammatory bowel disease in adults”. Gut 60 (2011): 571-607.
  10. Limketkai BN., et al. “Dietary interventions for induction and maintenance of remission in inflammatory bowel disease”. Cochrane Database of Systematic Reviews 2 (2019): CD012839.
  11. Obih C., et al. “Specific carbohydrate diet for pediatric inflammatory bowel disease in clinical practice within an academic IBD center”. Nutrition 32 (2016): 418-425.
  12. Cohen SA., et al. “Clinical and mucosal improvement with specific carbohydrate diet in pediatric Crohn disease”. Journal of Pediatric Gastroenterology and Nutrition 59 (2014): 516-521.
  13. Sigall-Boneh R., et al. “Partial enteral nutrition with a Crohn’s disease exclusion diet is effective for induction of remission in children and young adults with Crohn’s disease”. Inflammatory Bowel Disease 20 (2014): 1353-1360.
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Citation

Citation: Gim Hin Ho and Ee Ling Yeong Hazel. “Dietary Therapy in Adult Inflammatory Bowel Disease. Is there a Role in 2020?”.Acta Scientific Gastrointestinal Disorders 3.11 (2020): 01-03.




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