Celiac disease (CD) and inflammatory bowel diseases (IBD) are among the most common gastrointestinal disorders and share strong genetic risks that may predict their diagnosis or even guide their management, particularly the Human Leukocyte Antigen (HLA) system.

Historically, various associations between the HLA and autoimmune diseases were reported since the 1970s, and the HLA is now incriminated in a myriad of diseases including CD and IBD [1,2].

References

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9. Sazonovs A., et al. “HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease”. Gastroenterology 158.1 (2020): 189-199.
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Citation

Citation: Hakim Rahmoune., et al. “Back to the Future: HLA in Gastroenterology”. Acta Scientific Gastrointestinal Disorders 3.10 (2020): 01-02.

Copyright

Copyright: © 2020 Hakim Rahmoune., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.