Oral Submucous Firosis: An Update on Etiopathogenesis
Senior Research Associate, Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, MAMC Campus, New Delhi, India
*Corresponding Author: Shriya Khera, Senior Research Associate, Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, MAMC Campus, New Delhi, India.
Received: October 14, 2021; Published:00-00
The theories related to development of oral submucous fibrosis (OSMF) has been multifactorial. Many etiological factors include the consumption of areca nut (supari), betel leaves (paan), tobacco and intake of spicy food which are commonly found in asian foods. Systemic causes like nutritional deficiency, genetic predisposition, autoimmunity, heat shock proteins have also been proposed as causative factors for OSMF. Albeit the extensive documented aetiological factors, the precise etiology is not yet known and no conclusive evidence has been linked to the development and progression of Oral Submucous Fibrosis. The present review aims to decipher the various etiological agents and decoding their role in pathogenesis and progression of Oral Submucous Fibrosis.
Keywords: Oral Submucous Fibrosis; Areca Nut; Pathogenesis; Review
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