Odontogenic Keratocyst- Identity Unearthed: A Systematic Review
M S Nishanth1, Vishwas L1 and Gaurav2*
1Final Year Undergraduate Students, NSVK Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India
2Consultant Oral Physician and Maxillofacial Radiologist, Assistant Professor, Department of Oral Medicine and Maxillofacial Radiology, NSVK Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India
*Corresponding Author: Gaurav, Consultant Oral Physician and Maxillofacial Radiologist, Assistant Professor, Department of Oral Medicine and Maxillofacial Radiology, NSVK Sri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India.
Received: April 06, 2021; Published: May 17, 2021
Background: The odontogenic keratocyst (OKC) is a conundrumatic odontogenic cyst which is developmental in origin, commonly seen in the oral and maxillofacial region has gained traction since last two decades. This cyst is very distinctive because of its high recurrence rates and its aggressive behaviour; it also has characteristic clinical and histopathological features. The venture of classification of this cyst began in 1887, finally to WHO 2017. This cyst was formerly classified under the developmental odontogenic cyst of jaw in 1971 and 1992 by WHO. In the WHO classifications of head and neck tumors in 2005, OKC was renamed and reclassified as Keratocystic Odontogenic Tumor (KCOT), due to its aggressive nature and behaviour, specific histopathological characteristics and high recurrence rates. In the recent 2017 classification of HEAD AND NECK PATHOLOGY, KCOT was reclassified back into the category of CYSTS. Regardless of copious nomenclature and classifications of OKC, it is still challenging for the clinicians for identification, know the true nature, and its management.
Aim of the Study: To detect the significance and also describe and analyse the nomenclature of Odontogenic Keratocyst.
Materials and Methods: 30 articles were selected from the MEDLINE DATABASE having gone through the randomized control trial. 25 articles (studies) out of these were selected, which were best suitable for systematic review.
Result and Conclusion: We can say that the concepts of molecular pathophysiology of the OKC became clearer with advancements in scientific knowledge, various nomenclatures came forth and finally it has been accepted as a cyst today.
Keywords: Classification; Keratocyst; Odontogenic; Neoplasm; Mutation
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