Acta Scientific Dental Sciences (ASDS)(ISSN: 2581-4893)

Research Article Volume 5 Issue 2

The Authentic Inbred Sheath - “The Immunoglobulin"

Santhi Gorle1, Srikanth Adusumilli2, Rukmini Jyothirmayee Jakati3, Rani Ponnaganti1, Sahithi Valluripalli4 and Sanjeev V Jakati5*

1Senior Lecturer, KLR Lenora Institute of Dental Sciences, Rajahmundry, India

2Professor, Dr Sudha and Nageshwara Rao Siddhartha Institute of Dental Sciences, Vijaywada, India

3Senior Lecturer, Yogita Dental College and Hospital, Khed Ratnagiri, India

4Private Practioner, KLR Lenora Institute of Dental Sciences, Rajahmundry, India

5Reader, Yogita Dental College and Hospital, Khed Ratnagiri, India

*Corresponding Author: Sanjeev V Jakati, Reader, Yogita Dental College and Hospital, Khed Ratnagiri, India.

Received: December 02, 2020; Published: December 23, 2020

×

Abstract

Humans have developed a highly specialized defense mechanism system due to continuous stimulation by foreign material from the environment. Immunoglobulins are unique structures in the body which is synthesized by plasma cells and, to some extent, by lymphocytes. They have a significant role in recognizing and protecting the body against foreign material, either present freely in the body fluids or attached to cell surfaces. Besides the plasma, immunoglobulins may be identified in other body fluids or tissues such as urine, spinal fluid, milk, saliva, tears, lymph nodes, and spleen. The plasma cells and lymphocytes produce immunoglobulins at various stages of differentiation. Immunoglobulins represent a heterogeneous population to their Physico-chemical and biological properties. Immunoglobulins are divided into five classes IgG, IgA, IgM, IgD, and IgE, which are classified based on H chains.

Keywords: Immunoglobulins; Pathogens; Immunity

×

References

  1. J Mestecky. “Structure of antibodies”. Journal of Oral Pathology 1 (1972): 288-300.
  2. R Ananthanarayana and CKJ Paniker. Textbook of microbiology 7th ed: 85-91.
  3. Robert J Genco. “Immunoglobulins and periodontal disease”. Journal of Periodontology 41 (1970): 196-201.
  4. Jorgensen GH., et al. “Immunoglobulin A deficiency and oral health status: a case-control study”. Journal of Clinical Periodontology 37 (2010): 1-8.
  5. Sterin-Borda L., et al. “Autoantibodies to β1-adrenoceptors in human chronic periodontitis induce overexpression of fibroblast CD40 and trigger prostaglandin E2 generation”. Journal of Periodontal Research 44 (2009): 330-337.
  6. Casarin RCV., et al. “Levels of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, inflammatory cytokines and species-specific immunoglobulin G in generalized aggressive and chronic periodontitis”. Journal of Periodontal Research 45 (2010): 635-642.
  7. Colhoun HM., et al. “Antibodies to periodontal pathogens and coronary artery calcification in type 1 diabetic and nondiabetic subjects”. Journal of Periodontal Research 43 (2008): 103-110.
  8. Saraiva L., et al. “IgG sera levels against a subset of periodontopathogens and severity of disease in aggressive periodontitis patients: a crosssectional study of selected pocket sites”. Journal of Clinical Periodontology 41 (2014): 943-951.
  9. Trindade SC., et al. “Induction of interleukin (IL)-1b, IL-10, IL-8 and immunoglobulin G by Porphyromonas gingivalis HmuY in humans”. Journal of Periodontal Research 47 (2012): 27-32.
  10. Pushpa S., et al. “Correlation of salivary immunoglobulin A against lipopolysaccharide of Porphyromonas gingivalis with clinical periodontal parameters”. Contemporary Clinical Dentistry 6 (2015): 305-308.
  11. John M Liljestrand., et al. “Combining Salivary Pathogen and Serum Antibody Levels Improves Their Diagnostic Ability in Detection of Periodontitis”. Journal of Periodontology 85 (2014): 123-131.
  12. Rams TE., et al. “Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis subgingival presence, species-specific serum immunoglobulin G antibody levels, and periodontitis disease recurrence”. Journal of Periodontal Research 41 (2006): 228-234.
  13. Sakai Y., et al. “Porphyromonas gingivalis- specific IgG subclass antibody levels as immunological risk indicators of periodontal bone loss”. Journal of Clinical Periodontology 28 (2001): 853-859.
  14. Pussinen PJ., et al. “Periodontal pathogen carriage, rather than periodontitis, determines the serum antibody levels”. Journal of Clinical Periodontology 38 (2011): 405-411
  15. Lindsay M Hall., et al. “Levels of Serum Immunoglobulin G Specific to Bacterial Surface Protein A of Tannerella forsythia are Related to Periodontal Status”. Journal of Periodontology 2012 83 (2012): 228-234.
  16. Graswinckel JEM., et al. “Plasma antibody levels in periodontitis patients and controls”. Journal of Clinical Periodontology 31 (2004): 562-568.
  17. Apatzidou DA., et al. “Impact of smoking on the clinical, microbiological, and immunological parameters of adult patients with periodontitis”. Journal of Clinical Periodontology 32 (2005): 973-983.
  18. Hamdan S Al-Ghamdi and Sukumaran Anil. “Serum antibody levels in smoker and non smoker saudi subjects with chronic periodontitis”. Journal of Periodontology 78 (2007): 1043-1050.
  19. Decarlo AA., et al. “Serum antibodies against the hemoglobin-binding domain (HA2) of Porphyromonas gingivalis”. Journal of Periodontal Research 39 (2004): 228-235.
  20. Reena Kulshrestha., et al. “Role of immunoglobulin in periodontitis”. Journal of Pure and Applied Microbiology1 (2013): 673-676.
×

Citation

Citation: Santhi G., et al. “The Authentic Inbred Sheath - “The Immunoglobulin"". Acta Scientific Dental Sciences 5.2 (2021): 02-07.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days

Indexed In



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is November 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US









ff

© 2024 Acta Scientific, All rights reserved.