Acta Scientific Clinical Case Reports (ASCR)

Case Report Volume 6 Issue 4

Double Focal Compression Bandaging Technique: Enhancing Vascular Regeneration in the Lower Limbs

Carlos Sánchez Fernández de la Vega*

Fingoi Centre/Primary Care-Galego Health Service, Lugo, Spain

*Corresponding Author: Carlos Sánchez Fernández de la Vega, Fingoi Centre/Primary Care-Galego Health Service, Lugo, Spain.

Received: February 11, 2025; Published: March 18, 2025

Abstract

This article examines the macroscopic changes in both lower extremities of a patient with chronic venous insufficiency and severe comorbidities, including chronic renal failure and heart failure. Over a period of 25 months, from December 2022 until the patient became bedridden and was subsequently hospitalized due to progressive clinical deterioration and a poor prognosis—ultimately leading to death—the ulcers were treated exclusively with the double focal compression technique, while treatment for underlying conditions was maintained.

The primary objective of this study was to analyse the clinical course of the ulcers through a photographic sequence documenting their progression across various anatomical regions. Based on a retrospective analysis of previously treated cases, a dual hypothesis-physiological and physical-is proposed to interpret the observed outcomes. It is postulated that focal compression may activate physiological mechanisms such as angiogenesis and arteriogenesis, thereby promoting vascular regeneration. This effect may, in turn, be mediated by physical principles, particularly Pascal’s principle and the continuity equation for fluids, which could explain the redistribution of pressure and its impact on local perfusion. From this perspective, focal compression emerges as a therapeutic strategy with the potential to promote tissue regeneration and facilitate ulcer closure.

Method: For more than two decades, I have treated venous ulcers in over 200 patients using a compression bandage with gauze padding applied directly over the ulcer. This retrospective review documents consistent healing achieved solely through the pressure exerted by the bandage, without the need for adjunct therapies.

The cases included ulcers of varying sizes and complexities. Initially, elastic bandages were used, but they were later replaced with inelastic ones. Additional materials included gauze, adhesive tape, saline solution, and basic diagnostic tools such as a portable Doppler and monofilament.

Results: Findings presented at international conferences and published in peer-reviewed journals highlight the following key aspects:

  • The use of antibiotics was not required, as no infections occurred.
  • Debridement agents were unnecessary, as the technique itself promotes two types of debridement: autolytic and mechanical.
  • Effectiveness was observed in patients with severe peripheral arterial disease (Ankle-Brachial Index ≥ 0.6).
  • In patients who started treatment in the early stages of the disease, ulcer closure occurred within an average of 6 to 8 weeks.
  • Ulcer recurrence depended on the degree of vascular deterioration, emphasizing the importance of strong compression stockings after ulcer closure.
  • Favourable outcomes were noted in patients with mild-to-moderate heart failure, with no episodes of decompensation and improved mobility and quality of life.
  • Enhanced skin integrity and aesthetic appearance were observed, particularly in patients treated with compression over surgical sutures, where a reduction in perilesional inflammation and more homogeneous healing was noted.

It is hypothesized that these outcomes may be linked to the stimulation of angiogenesis and arteriogenesis due to the redistribution of pressure induced by focal compression. This effect is supported by physical principles such as Pascal’s principle and the continuity equation for fluids, which may explain improved tissue perfusion and the activation of regenerative processes. However, while these mechanisms are physiologically plausible, it is essential to validate these findings through large-scale controlled studies, including comparative clinical trials with standard therapies such as multilayer compression bandaging or negative pressure therapy. A precise characterization of the effects of focal compression would help establish its potential as a first-line treatment for various clinical conditions.

Keywords: Vascular Leg Ulcers; Double Focal Compression Bandaging; Angiogenesis; Arteriogenesis; Chronic Venous Insufficiency

References

  1. Wittens C., et al. “Management of Chronic Venous Disease: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS)”. European Journal of Vascular and Endovascular Surgery6 (2015): 678-737.
  2. O’Donnell TF., et al. “Management of venous leg ulcers: Clinical practice guidelines of the Society for Vascular Surgery (SVS) and the American Venous Forum (AVF)”. Journal of Vascular Surgery: Venous and Lymphatic Disorders6 (2020): 1063-1103.
  3. Nelzén O. “Forty years of treating venous leg ulcers: The role of compression and how much is needed”. Journal of Wound Care5 (2017): 195-200.
  4. González-Consuegra RV and Verdú J. “Quality of life in people with venous leg ulcers: an integrative review”. Journal of Advanced Nursing5 (2011): 926-944.
  5. Adams RH and Alitalo K. “Molecular regulation of angiogenesis and lymphangiogenesis”. Nature Reviews Molecular Cell Biology6 (2007): 464-478.
  6. Ribatti D and Crivellato E. “Sprouting angiogenesis’, a reappraisal”. Developmental Biology2 (2020): 126-135.
  7. Tonnesen MG., et al. “Angiogenesis in wound healing”. Journal of Investigative Dermatology Symposium Proceedings 1 (2000): 40-46.
  8. Carmeliet P and Jain RK. “Molecular mechanisms and clinical applications of angiogenesis”. Nature 7347 (2011): 298-307.
  9. Schirmer SH., et al. “Stimulation of collateral artery growth: travelling further down the road to clinical application”. Heart3 (2009): 191-197.
  10. Siddiqui AH., et al. “Mechanisms of arteriogenesis and their therapeutic implications”. Frontiers in Cardiovascular Medicine 8 (2021): 634983.
  11. Hinkle MM., et al. “Advances in peripheral artery disease revascularization: A novel perspective on therapeutic angiogenesis and arteriogenesis”. Circulation Research 6 (2020): 789-803.
  12. Potente M., et al. “Basic and therapeutic aspects of angiogenesis”. Cell 6 (2011): 873-887.
  13. Mani R. “Topical oxygen therapy for chronic wounds: a report on the potential of NATROX, a new device for delivering enriched oxygen to chronic wounds”. Journal of Wound Technology3 (2010): 28-30.
  14. Sánchez Fernández de la Vega C. “Venous leg ulcers”. Double focal compression bandaging”. Conference: October (2005).
  15. Sánchez Fernández de la Vega C. “Focalized pressure on the wound bed prevents infection. Double focal compression bandaging”. International Journal of Information Research and Review10 (2020): 7113-7120.
  16. Sánchez Fernández de la Vega C. “Bacterial contamination does not necessarily mean infection”. International Journal of Angiology1 (2010).
  17. Sánchez Fernández de la Vega C. “Focused pressure over the surgical wound, improves the aesthetic outcome”. International Journal of Information Research and Review9 (2021): 7352-7355.
  18. Johnson M and Lee T. “Compression Therapy in Wound Management: A Review of Current Evidence”. Journal of Wound Care4 (2022): 217-223.
  19. Smith A., et al. “Evaluating the Efficacy of Elastic vs. Inelastic Bandages for Ulcer Treatment”. International Journal of Dermatology2 (2023): 105-112.
  20. Partsch H., et al. “Measurement of lower leg compression in vivo: recommendations for the performance of measurements of interface pressure and stiffness: consensus statement”. Dermatology Surgery2 (2022): 224-232; discussion 233.
  21. Thomas S and Fram P. “Laboratory-based evaluation of a compression-bandaging system”. Nursing Times40 (2003): 24-28.
  22. Partsch H. “The use of pressure changes on standing as a surrogate measure of the stiffness of a compression bandage”. European Journal of Vascular and Endovascular Surgery4 (2004): 415-421.
  23. Lee AJ., et al. “Compression therapy: effects of posture and application techniques on initial pressures delivered by bandages of different physical properties”. European Journal of Vascular and Endovascular Surgery5 (2006): 542-552.
  24. Hafner J., et al. “A comparison of multilayer bandage systems during rest, exercise, and over 2 days of wear time”. Archives of Dermatology7 (2000): 857-863.
  25. Barbanel JC., et al. “In vivo and laboratory evaluation of elastic bandages”. Care Science Practice 8 (1990): 75-79.
  26. Partsch H., et al. “The Static Stiffness Index: an important parameter to characterise compression therapy in vivo”. Journal of Wound Care 25 (2016): S4-S10.
  27. Lundh T and Damm J. “The Lundatex System: A cohesive bandage for venous issues”. Journal of Phlebology2 (2016): 23-30.
  28. PressCise AB. “Lundatex System”. Retrieved from PressCise website (2016).
  29. Smith R and Johnson L. “Innovations in cohesive bandaging for venous ulcers”. Wound Care1 (2018): 12-18.
  30. International Union of Phlebology. “Awards for Excellence in Phlebology”. Retrieved from IUP website (2020).
  31. Johnson M and Lee P. “Advances in treatment of venous insufficiency”. Phlebology Today4 (2021): 55-60.
  32. Mosti G and Partsch H. “A New Two Component Compression System Turning an Elastic Bandage into an Inelastic Compression Device: Interface Pressure, Stiffness, and Haemodynamic Effectiveness”. European Journal of Vascular and Endovascular Surgery1 (2018): 126-131.
  33. Partsch H., et al. “The Static Stiffness Index: an important parameter to characterise compression therapy in vivo”. Journal of Wound Care9 (2016): S4-S10.
  34. Guven H. “Fluid dynamics and venous hemodynamics in the lower extremities”. Vasa5 (2004): 308-313.
  35. Schuren J and Mohr K. “Pascal's law and the dynamics of compression therapy: a study on healthy volunteers”. International Angiology5 (2010): 431-435.
  36. Berszakiewicz A., et al. “Compression therapy in venous diseases: physical assumptions and clinical effects”. Postepy Dermatologii I Alergologii6 (2020): 842-847.

Citation

Citation: Carlos Sánchez Fernández de la Vega. “Double Focal Compression Bandaging Technique: Enhancing Vascular Regeneration in the Lower Limbs". Acta Scientific Clinical Case Reports 6.4 (2025): 10-26.

Copyright

Copyright: © 2025 Carlos Sánchez Fernández de la Vega. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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