ACTA SCIENTIFIC CLINICAL CASE REPORTS

Case Report Volume 5 Issue 3

Treatment of Cuboid Bone Osteomyelitis in Diabetic Patient with Bioactive Glass S53P4 – Case Report

Janežič Lea Dora1, Križaj Julija1 and Frangež Igor1,2*

1Department of Surgical Infections, University Medical Center Ljubljana, Slovenia
2Faculty of Medicine, University of Ljubljana, Slovenia

*Corresponding Author: Frangež Igor, Assistant Professor, Department of Surgical Infections, University Medical Center Ljubljana, Slovenia.

Received: January 31, 2024; Published: February 11, 2024

Abstract

Osteomyelitis in diabetic patients requires a very challenging treatment and often leads to limb amputation. Due to increasing incidence of diabetes it has become a worldwide health problem. There have been few cases in the literature described as successful treatment of cuboid osteomyelitis with a new bone substitute as Bioactive Glass S53P4. We present a clinical case of diabetic patient with an osteomyelitis of cuboid bone due to chronic foot ulcer where a two-stage surgical treatment was indicated with a suitable antibiotic treatment. Firstly, a resection of infected bone was done with a temporary antibiotic spacer and arthrodesis was made and a second part with a Bioactive Glass substitute and treating the ulcer with a half thickness skin graft. In our clinical case treatment with Bioactive Glass in diabetic osteomyelitis showed successful results with a promising treatment outcome.

Keywords: Diabetic Foot; Osteomyelitis; Cuboid Bone; Bioactive Glass; Surgical Treatment

References

  1. Hosseinzadeh A., et al. “Foot Ulcer”. PubMed, StatPearls Publishing (2022).
  2. Senneville E., et al. “IWGDF/IDSA Guidelines on the Diagnosis and Treatment of Diabetes-related Foot Infections (IWGDF/IDSA 2023)”. Infectious Disease Society of America, Clinical Infectious Diseases (2023).
  3. Panunzi A., et al. “Bioactive glass in a multi drug resistance osteomyelitis in Diabetic Foot: Case Report”. The International Journal of Lower Extremity Wounds (2022): 153473462211026.
  4. De Giglio R., et al. “Efficacy and Safety of Bioactive Glass S53P4 as a Treatment for Diabetic Foot Osteomyelitis”. The Journal of Foot and Ankle Surgery (2020).
  5. Korpar I and Frangež I. “Preservation Surgery of Septic Osteoarthritis and Osteomyelitis in the Diabetic Foot Using S53P4 Bioactive Glass—a Case Series”. Applied Science 5 (2023): 3310-3310.
  6. Vasiliadis ES., et al. “Two Stage Surgical Treatment of Cuboid Osteomyelitis. A Case Report and Review of the Literature”. The Foot 47 (2021): 101796.
  7. Kastrin M., et al. “Possible Advantages of S53P4 Bioactive Glass in the Treatment of Septic Osteoarthritis of the First Metatarsophalangeal Joint in the Diabetic Foot”. Journal of Clinical Medicine6 (2021): 1208.

Citation

Citation: Frangež Igor., et al. “Treatment of Cuboid Bone Osteomyelitis in Diabetic Patient with Bioactive Glass S53P4 – Case Report".Acta Scientific Clinical Case Reports 5.3 (2024): 37-41.

Copyright

Copyright: © 2024 Frangež Igor., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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