ACTA SCIENTIFIC CLINICAL CASE REPORTS

Case Report Volume 5 Issue 3

NT-pro BNP - Important Screening Tool for Perioperative Risk Assessment

Itee Chowdhury1*, Soumi Pathak2 and Sangeeta Bhagat3

1Senior Consultant, Rajiv Gandhi Cancer Institute and Research Centre, DA, DNB Anaesthesia, Delhi, Presently Max Institute of Cancer Care SHBG, India
2Consultant Anaesthesia, Rajiv Gandhi Cancer Institute and Research Centre, MD Anaesthesia, Delhi, India
3Attending Consultant, Rajiv Gandhi Cancer Institute and Research Centre, DA, DNB Anaesthesia, Delhi, India

*Corresponding Author: Itee Chowdhury, Senior Consultant, Rajiv Gandhi Cancer Institute and Research Centre, DA, DNB Anaesthesia, Delhi, Presently Max Institute of Cancer Care SHBG, India.

Received: January 16, 2024; Published: February 05, 2024

Abstract

Background: NT pro BNP is a prognostic marker for patients with heart failure (HF) and chronic kidney disease (CKD). The implication of excessively high (≥4000 pg/ml) NT pro BNP levels is still a highly debatable topic. However, such values cannot be ignored and must be taken note of as an impending heart failure if already not so in a preanaesthetic check up and treated aggressively. We present here a case report to highlight this issue.

Case: A 76 years old female, known case of CAD, nephrotic syndrome and CKD, diagnosed carcinoma breast, was posted for Breast conserving surgery and oncoplasty. On examination she did not have any signs and symptoms of heart failure (HF). Left ventricular ejection fraction was 30% and she had critically low GFR (15ml/min/1.73m2). Her preanaesthetic work up included NT pro BNP levels which was 4310 pg/ml. She was aggressively treated with frusemide, B blocker and vasodilators. Maintaining a balance between her preload and after load was the key to the successful intraoperative management of this patient.

Conclusion: High NT pro BNP in patients with no signs and symptoms of HF must not be ignored as it may be the only indicator of the impending heart failure.

Keywords: Heart Failure; Renal Insufficiency; Chronic; Breast Neoplasms

References

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  2. Nakagawa O., et al. “Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an “emergency” cardiac hormone against ventricular overload”. Journal of Clinical Investigation 96 (1995): 1280-1287.
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  4. Maisel AS., et al. “Utility of B-natriuretic peptide as a rapid, point-of-care test for screening patients undergoing echocardiography to determine left ventricular dysfunction”. American Heart Journal 141 (2001): 367-374.
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  8. DeFilippi C., et al. “Amino-terminal pro-B-type natriuretic peptide testing in renal disease”. American Journal of Cardiology 101 (2008): 82-88.

Citation

Citation: Itee Chowdhury., et al. “NT-pro BNP - Important Screening Tool for Perioperative Risk Assessment".Acta Scientific Clinical Case Reports 5.3 (2024): 19-21.

Copyright

Copyright: © 2024 Itee Chowdhury., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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