ACTA SCIENTIFIC CLINICAL CASE REPORTS

Research Article Volume 5 Issue 1

Practically Achievable Accuracy and Uncertainties Estimation in Radiation Dose Measurement with Different Protocols

Kamanzi J D1*, Md Akhtaruzzaman2, Penabei Samafou3, Laurent Rangira1, Sy Khady4, Uwitonze Emmanuel1, Gahimano J B1 and Bugingo Samuel5

1Department of Radiation Oncology, Rwanda Cancer Centre, Kigali, Rwanda
2Department of Radiation Oncology, Evercare Hospital Chattogram, Bangladesh
3Faculty of Medicine and Health Sciences, University of Sherbrooke, Quebec, Canada
4Cheikh Anta Diop University, Dakar, Senegal
5Diagnostic Radiology Department, King Faisal Hospital, Rwanda

*Corresponding Author: Kamanzi J D, Department of Radiation Oncology, Rwanda Cancer Centre, Kigali, Rwanda.

Received: November 07, 2023; Published: December 26, 2023

Abstract

Aim: This study aimed to determine the degrees of accuracy that are practically achievable in dose measurement with reference to the international protocols and estimated the associated uncertainties.

Material and Method: Experiments were performed on Varian linac with 5 photon energies; 6, 10, 15 MV, and 6, 10, MV Flattening Filter Free. Tissue phantom ratio (TPR20,10), percent depth dose (%DD) were measured and calculated, while beam profile was only measured. Measurements for range of field sizes and depths were carried out in water with Farmer and Semiflex chambers.

Results: The measured TPR20,10 values were in agreement with calculations, where percentage error was found to be < 0.6% for all energies. The absorbed dose to water (Dw,Q) at zmax according to Task Group (TG)-51, and Technical Reports Series (TRS)-398 protocols was in good agreement with an average discrepancy of <0.2%. The observed discrepancies were thought to be associated with procedures and equipment used. The percentage difference between monitor units (MUs) delivered by linac and MUs calculated by Treatment Planning System (TPS) at 5 and 10 cm depths for various field sizes were found to be within ± 5% tolerance limit. The measured %DD are consistent with calculations from TPS. The relative standard uncertainty of Dw,Q at reference depth in water, was also found as ±<2.0%.

Conclusion: Overall, the results of measured parameters were in acceptable agreement as per recommended protocols, and measurements are consistent with calculations from TPS. This assisted to move forward with beam modelling of the TPS.

Keywords: Accuracy; Uncertainties; Photon; Dosimetry; Protocols

References

  1. Mijnheer BJ., et al. “What degree of accuracy is required and can be achieved in photon and neutron therapy?” Radiotherapy Oncology 8 (1987): 237-252.
  2. International Atomic Energy Agency. Standards, Applications and Quality Assurance in Medical Radiation Dosimetry (IDOS): Accuracy requirements in medical radiation dosimetry 1 (2011): 29.
  3. Brahme A. “Dosimetric precision requirements in radiation therapy”. Acta Radiologica: Oncology 23 (1984): 379-391.
  4. Thwaites D. “Accuracy required and achievable in radiotherapy dosimetry: have modern technology and techniques changed our views?” Journal of Physics: Conference Series 444 (2013).
  5. Jacob V D., et al. “Accuracy and Uncertainty Considerations in Modern Radiation Oncology”. In The Modern Technology of Radiation Oncology, third edition 41.12 (2013).
  6. International Commission on Radiation Units and Measurements (ICRU). “Determination of absorbed dose in a patient irradiated by beams of X or gamma rays in radiotherapy procedures”. ICRU report 24, Journal of the ICRU 13.1 (1976).
  7. International Organization for Standardization. Uncertainty of measurement - Part 3: Guide to the expression of uncertainty in measurement (GUM: 1995), ISO/IEC Guide 98-3:2008, ISO, Geneva (1995).
  8. Debbie VM., et al. “Accuracy requirements and uncertainties in radiotherapy: a report of the International Atomic Energy Agency”. Acta Oncologica (2017).
  9. Ethel SG. “The impact of dosimetry uncertainties on dose response analyses”. Health Physics5 (2009): 487-492.
  10. Almond PR., et al. “AAPM’s TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams”. Medical Physics9 (1999): 1847-1870.
  11. International Atomic Energy Agency. Technical Reports Series No. 398. Absorbed Dose Determination in External Beam Radiotherapy: An International Code of Practice for Dosimetry Based on Standards of Absorbed Dose to Water IAEA, Vienna (2000).
  12. DIN 6800-2. Dosismessverfahrennach der SondenmethodefürPhotonen- und Elektronenstrahlung - Teil 2: DosimetriehochenergetischerPhotonen- und ElektronenstrahlungmitIonisationskammern (2008).
  13. Institute of Physics and Engineering in Medicine (IPEM). “Code of practice for high-energy photon therapy dosimetry based on the NPL absorbed dose calibration service”. Physics in Medicine and Biology 65 (2020): 195006.
  14. Followill DS., et al. “An empirical relationship for determining photon beam quality in TG-21 from a ratio of percent depth doses”. Medical Physics 25 (1998): 1202-1205.
  15. Netherlands Commission on Radiation Dosimetry (NCS). “Code of Practice for the Absorbed Dose Determination in High Energy Photon and Electron Beams”. Report 18, 2012, Delft, Netherlands (2012).
  16. International Electrotechnical Commission (IEC): Medical electrical equipment-Medical electron accelerators-Guidelines for functional performance characteristics. Technical Reports (TR)-60977.
  17. Romagnoli R., et al. “Comparison of different methods for output factor measurements on 10 MeV Linac”. Radiation Oncology 99 (2011): S24.

Citation

Citation: Kamanzi J D., et al. “Practically Achievable Accuracy and Uncertainties Estimation in Radiation Dose Measurement with Different Protocols". Acta Scientific Clinical Case Reports 5.1 (2024): 56-62.

Copyright

Copyright: © 2024 Kamanzi J D., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days

Indexed In



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US