Acta Scientific Clinical Case Reports

EditorialVolume 4 Issue 6

Determination of ACE gene polymorphism among COVID-19 Patients as Predictive Marker of Increased Risk of Thrombosis

Mustafa Ibrahim Abbas1, Mai Shakir Mohammed1 and Khalid Abdelsamea Mohamedahmed1,2*

1Department of Hematology and Immunohematology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan
2Department of Immunology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan

*Corresponding Author: Khalid Abdelsamea Mohamedahmed, Department of Hematology and Department of Immunology, Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan.

Received: January 27, 2023; Published: May 01, 2023

The highly contagious new human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coagulopathies are now recognized as major causes of mortality. SARS-CoV-2 may be a highly prothrombotic virus that alters the coagulation cascade in unknown ways, causing a steady rise in D-dimer as the severity and extent of micro thrombosis rises [1].

Keywords: Angiotensin-Converting Enzyme (ACE); Thrombosis; COVID-19

Bibliography

  1. Mohammed MS and Mohamedahmed KA. “Heme Oxygenase-1 (HMOX1) Gene Polymorphisms as Predictive Markers of Increased Risk of Thrombosis among Patients with COVID-19”. GMJ 11 (2022): e2398.
  2. Holcomb D., et al. “Gene variants of coagulation related proteins that interact with SARS-CoV-2”. PLOS Computational Biology 3 (2021): e1008805.
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  4. Li P., et al. “Factors Associated With Risk of Postdischarge Thrombosis in Patients With COVID-19”. JAMA Network Open11 (2021): e2135397.
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  6. Mohamedahmed KA., et al. “Thrombocytopenia as diagnostic and prognostic biomarker for severity of COVID-19 infection”. Edorium Journal of Infectious Diseases 5 (2021): 100013I03KM2021.
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  8. Karakaş Çelik S., et al. “Polymorphisms of ACE (I/D) and ACE2 receptor gene (Rs2106809, Rs2285666) are not related to the clinical course of COVID-19: A case study”. Journal of Medical Virology10 (2021): 5947-5952.
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  10. Oscanoa TJ., et al. “ACE gene I/D polymorphism and severity of SARS-CoV-2 infection in hospitalized patients: a meta-analysis”. Arterial Hypertense3 (2012): 112-118.

Citation: Khalid Abdelsamea Mohamedahmed., et al. “Determination of ACE gene polymorphism among COVID-19 Patients as Predictive Marker of Increased Risk of Thrombosis". Acta Scientific Clinical Case Reports 4.6 (2023): 01-02.

Copyright: © 2023 Khalid Abdelsamea Mohamedahmed., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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