Acta Scientific Clinical Case Reports

Case ReportVolume 4 Issue 4

Cardiopulmonary Exercise Testing and Metabolic Myopathy as a Cause of Dyspnea: A Case Report

Behsarat Rahimi MD1, Maryam Edalatifar MD2, Hossein Kazemizadeh MD3, Forough Kalantari MD4 and Elham Kalantari MD 5

1,2,3Advanced Thoracic Research Center, Occupational Sleep Research Center, Tehran University of Medical Sciences, Tehran, Iran
4Department of Nuclear Medicine, school of Medicine, Iran University of medical science, Iran
5Department of Pulmonology, School of Medicine, Isfahan University of Medical Science, Iran

*Corresponding Author: Elham Kalantari MD, Department of Pulmonology, School of Medicine, Isfahan University of Medical Science, Iran.

Received: February 17, 2023; Published: March 07, 2023

Abstract

Clinical presentation of Mitochondrial disease is wide due to different organs involved in it. When skeletal muscle is affected, the term mitochondrial myopathy is used. Exercise limitation is among symptoms affecting patients with myopathy. In approaching dyspnea Establishing an accurate diagnosis is essential because treatment depends on the underlying condition. The case we report is a patient with chronic dyspnea in whom evaluated through cardiopulmonary exercise test and metabolic myopathy was identified.

Keywords: Mitochondrial Disease; Dyspnea; Cardiopulmonary Exercise Test (CPET)

Bibliography

  1. Luks A and Glenny R. Clinical exercise testing in: Courtney V, Murray and nadel’ s Text book of respiratory medicine. 6th Elsevier saunders (2016): 436.
  2. “What is mitochondrial disease?”
  3. Arpa J., et al. “Prevalence and progression of mitochondrial diseases: a study of 50 patients”. Muscle Nerve 28 (2003): 690-695.
  4. Gorman GS., et al. “Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease”. Annals of Neurology 77 (2015): 753-759.
  5. Nishigaki Y., et al. “Exercise-induced muscle “burning,” fatigue, and hyper-CKemia: mtDNA T10010C mutation in tRNA(Gly)”. Neurology 58 (2002): 1282-1285.
  6. Hirata K., et al. “Adult onset limb-girdle type mitochondrial myopathy with a mitochondrial DNA np8291 A-to-G substitution”. Journal of Human Genetics 44 (1999): 210-214.
  7. “ATS/ACCP Statement on Cardiopulmonary Exercise Testing”.
  8. Heinicke K., et al. “Exertional dyspnea in mitochondrial myopathy: clinical features and physiological mechanisms”. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 301 (2011): R873-R884.
  9. Taivassalo T., et al. “The spectrum of exercise tolerance in mitochondrial myopathies: a study of 40 patients”. Brain 126 (2003): 413-423.

Citation: Elham Kalantari MD., et al. “Cardiopulmonary Exercise Testing and Metabolic Myopathy as a Cause of Dyspnea: A Case Report". Acta Scientific Clinical Case Reports 4.4 (2023): 22-25.

Copyright: © 2022 Elham Kalantari MD., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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