Acta Scientific Clinical Case Reports

Case ReportVolume 3 Issue 10

A Case Report of Wernicke’s Encephalopathy in a Patient with Sepsis

A Deepa1 and Rajendra Prasad2*

1PG, Department of Clinical Case Reports, India
2Assistant Professor, Department of Clinical Case Reports, India

*Corresponding Author: Rajendra Prasad, Assistant Professor, Department of Clinical Case Reports, India.

Received: August 19, 2022; Published: September 02, 2022


Thiamine (vitamin B1) deficiency is rare but if it occurs can cause vague symptoms like loss of appetite, fatigue, sleep disturbances to severe neurological disorders like polyneuropathy, Wernicke’s encephalopathy and korsakoffs syndrome and Cardiovascular manifestations like high output cardiac failure primarily in alcoholics. Many patients with sepsis, critical illness develop altered mental states, variously described as disorientation, confusion, delirium and encephalopathy without obvious explanation.

We report a case of wernickes encephalopathy in sepsis with acute kidney injury in a 36 year old male who is chronic alcoholic without other Comorbidities who presented with high grade fever, vomiting’s since 3 days, altered sensorium and difficulty in walking since 1 day. Leucocyte count was elevated on hemogram, renal function tests were abnormal suggesting acute kidney injury, ESR and CRP were raised. MRI findings were suggestive of Wernicke’s encephalopathy and there was significant improvement in symptoms after thiamine supplementation.

Keywords: Thiamine; Leucocyte; Wernicke’s Encephalopathy


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Citation: A Deepa and Rajendra Prasad. “A Case Report of Wernicke’s Encephalopathy in a Patient with Sepsis". Acta Scientific Clinical Case Reports 3.10 (2022): 10-11.

Copyright: © 2022 A Deepa and Rajendra Prasad. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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