Acta Scientific Clinical Case Reports

Case ReportVolume 3 Issue 9

Multiple System Atrophy in a Filipino 36-year-old Female Presenting as Progressive Gait Ataxia - A Case Report

Meleza Mea B Cambalon and Luis C Lagarde*

Graduate of Neurology in Philippines

*Corresponding Author: Luis C Lagarde, Graduate of Neurology in Philippines.

Received: August 01, 2022; Published: August 25, 2022

Abstract

Multiple system atrophy (MSA) is a rare, progressive, fatal, neurodegenerative disorder with incidence and prevalence of 0.6 to 0.7 cases per 100,000 and 3.4 to 4.9 cases per 100,000 population, respectively [1]. This is a case of a 36-year-old woman presenting with predominant features of gait ataxia. On imaging, there was marked cerebro-cerebellar atrophy more prominent in the cerebellum.

Keywords: Multiple system atrophy (MSA); Covid-19; Hypertension

Bibliography

  1. Fanciulli A and Wenning GK. “Multiple-system atrophy”. The New England Journal of Medicine 3 (2015): 249-263.
  2. Roncevic D., et al. “Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival”. Journal of Neural Transmission (Vienna) 121 (2014): 507-512.
  3. Quinn N. “A short clinical history of multiple system atrophy”. Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society 25 (2015): 3-7.
  4. Mendoza-Santiesteban CE., et al. “The Retina in Multiple System Atrophy: Systematic Review and Meta-Analysis”. Frontiers in Neurology 8 (2017a): 206.
  5. Palma JA., et al. “Prevalence of REM sleep behavior disorder in multiple system atrophy: a multicenter study and meta-analysis”. Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society 25 (2015): 69-75.
  6. Petrovic IN., et al. “Multiple system atrophy-parkinsonism with slow progression and prolonged survival: a diagnostic catch”. Movement Disorders: Official Journal of the Movement Disorder Society 27 (2012): 1186-1190.
  7. Palma Jose-Alberto., et al. “Diagnosis of multiple system atrophy”. Autonomic Neuroscience: Basic and Clinical 211 (2018): 15-25.
  8. Lin DJ., et al. “Multiple system atrophy of the cerebellar type: clinical state of the art”. Movement Disorder 29 (2014): 294-304.
  9. Fanciulli Alessandra., et al. “Multiple System Atrophy”. International Review of Neurobiology 149 (2019): 137-192.
  10. Gilman S., et al. “Second consensus statement on the diagnosis of multiple system atrophy”. Neurology 71 (2008): 670-676.
  11. Singer Wolfgang., et al. “Alpha-Synuclein Oligomers and Neurofilament Light Chain in Spinal Fluid Differentiate Multiple System Atrophy from Lewy Body Synucleinopathies”. Annals of Neurology3 (2020): 503-512.

Citation: Meleza Mea B Cambalon and Luis C Lagarde. “Multiple System Atrophy in a Filipino 36-year-old Female Presenting as Progressive Gait Ataxia - A Case Report". Acta Scientific Clinical Case Reports 3.9 (2022): 65-67.

Copyright: © 2022 Meleza Mea B Cambalon and Luis C Lagarde. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US