Acta Scientific Clinical Case Reports

Case ReportVolume 3 Issue 9

Suspected Parkinsonism Following COVID-19 Infection

Sam Kara1*, Reza S Roghani2, Pamela Youssef1 and Kester Nedd1

1Department of Neurology, Larkin Community Hospital Palm Springs Campus, Miami, Florida, USA
2Department of Physical Medicine and Rehabilitation, Larkin Community Hospital South Campus, Miami, Florida, USA

*Corresponding Author: Sam Kara, Department of Neurology, Larkin Community Hospital Palm Springs Campus, Miami, FL 33012, USA,

Received: August 01, 2022; Published: August 19, 2022


Neurological complications, both acute and long- term, have been reported during the COVID-19 infection pandemic. Aside from idiopathic Parkinson's disease (PD), there are rare presentations of atypical parkinsonian syndromes. Infection, as an etiology, leading to PD or parkinsonism is rare. However, this hypothesis gained more traction as a result of the few cases reported during the COVID-19 pandemic. To date, less than a handful of reports describe parkinsonian type disease complications following COVID-19 infection. These cases, including this report, are important to establish the exact etiology and demographics (sex, age, and race) for this devastating COVID-19 sequelae. The COVID-19 virus was found to infiltrate and impact the central nervous system (CNS) through hematogenous and lymphatic routes, and through the cribriform plate via the olfactory bulb. These cases help to delineate the risk factors, improve our understanding of the duration and course of disease, treatment options, and solidify our knowledge of comorbidities affecting the presentation. We present a case of acute parkinsonism post-COVID-19 infection in an immunocompetent female. A brain Magnetic resonance imaging (MRI) revealed lesions in both the white matter and Globus palladium changes. All lesions had homogeneous contrast enhancement without any sign of hemorrhage, and affecting mostly the supratentorial punctiform and pontine areas. Patient symptoms improved on a trial of levodopa-carbidopa.

Keywords: Parkinson’s Disease; Parkinsonism; COVID-19; Tremor; Levodopa


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Citation: Sam Kara., et al. “Suspected Parkinsonism Following COVID-19 Infection". Acta Scientific Clinical Case Reports 3.9 (2022): 51-55.

Copyright: © 2022 Sam Kara., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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