EN Okpukpu*, SA Wemedo and T Sampson

Department of Microbiology, Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Nigeria

*Corresponding Author: EN Okpukpu, Department of Microbiology, Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Nigeria.

Received: July 25, 2022; Published: August 09, 2022

Abstract

Infection of wounds is a common, often severe and costly complication resulting from bacterial colonization. The aim of this study was to investigate the prevalence and antibiotics susceptibility pattern of Pseudomonas aeruginosa in wounds of patients attending a tertiary hospital in Port Harcourt. One hundred and fifty (150) samples from wounds in different hospital wards were collected by using sterile cotton swab sticks. The specimen were taken to the Microbiology Laboratory, Rivers State University, Port Harcourt, Nigeria, for microbiological analysis, using Standard procedures for cultural characterization. Antibiotics sensitivity was evaluated using the Kirby-Bauer disc diffusion method. Data showed that Burns had the highest percentage occurrence of 24%, followed by Caesarean section (21%). Scrotal wounds had a percentage occurrence of 17%. Accident and Emergency (A/E) and Plastic Surgery both had a percentage occurrence of 10% each, while traumatic wounds and surgical wounds had a percentage occurrence of 7% each. The least occurrence was seen in Dermatomytosis Ward (DMS) with percentage occurrence of 4%. The study further revealed that the highest incidence of wound infection (55%) was associated with the female gender compared to the male gender having a percentage occurrence of 45%. The antimicrobial susceptibility test showed that 96.30% of the isolates were resistant to Cefuroxime, while 92.59% and 85.19% of the isolates were resistant to Augmentin and Cefixime, respectively. In the case of Gentamycin, there was a moderate level of resistance, with 51.85% of the isolates being resistant. Ceftazidime and Ofloxacin both had lower resistance profile, with 48.15% of the isolates showing resistance. The highest growth inhibition was seen in Ciprofloxacin, with only 37.04% of the isolates showing resistance. The high level of antibiotics resistance by Pseudomonas aeruginosa associated with wound colonization in this study is of a serious concern. Therefore the need for proper wound management in the hospital environment cannot be overemphasized.

Keywords: Antibiotics Susceptibility; Prevalence; Pseudomonas aeruginosa; Wound Infection; Port Harcourt

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Citation: EN Okpukpu., et al. “Prevalence and Antibiotics Susceptibility Profile of Pseudomonas aeruginosa Associated with Wound Infections in Port Harcourt, Nigeria". Acta Scientific Clinical Case Reports 3.9 (2022): 04-10.

Copyright: © 2022 EN Okpukpu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.