Acta Scientific Clinical Case Reports

Case ReportVolume 3 Issue 7

Miller Fisher Syndrome and Acute Motor and Sensory Axonal Neuropathy (AMSAN) Variant Guillain-Barré Overlap Syndrome (MFS/AMSAN-GBS) After Upper Respiratory Tract Infection (URTI)

Tan Chun Chau* and Nik Azlan Nik Muhamad

Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Kuala Lumpur, Malaysia

*Corresponding Author: Tan Chun Chau, Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Kuala Lumpur, Malaysia.

Received: February 22, 2022; Published: June 02, 2022

Abstract

A 50-year-old woman was admitted to the emergency room (ED) with progressive weakness and ascending numbness of the body, back pain, dysphagia, and diplopia for two days. The neurological findings were preceded by an upper respiratory tract infection. Subsequently, severe weakness of the bulbar and limb muscles, areflexia, and ophthalmoplegia developed. Based on clinical features, Miller-Fisher syndrome (MFS) was diagnosed, while a nerve conduction study revealed an overlap with acute motor-sensory axonal neuropathy (AMSAN) variant Guillain-Barré syndrome (MFS/AMSAN-GBS). The panel of anti-ganglioside antibodies was positive. Early treatment with intravenous immunoglobulin favored the outcome.

Keywords: Demyelinating Disease; Polyneuropathies; Guillain-Barré Syndrome; Miller Fisher Syndrome

Bibliography

  1. McGrogan A., et al. “The epidemiology of Guillain-Barré syndrome worldwide”. Neuroepidemiology 2 (2009): 150-163.
  2. Willison HJ., et al. “Guillain-Barré syndrome”. The Lancet10045 (2016): 717-727.
  3. Papathanasiou A and Markakis I. “Clinical heterogeneity of Guillain-Barré syndrome in the emergency department: Impact on clinical outcome”. Case Reports in Emergency Medicine 2016 (2016).
  4. Bukhari S and Taboada J. “A case of Miller Fisher syndrome and literature review”. Cureus 2 (2017).
  5. Dowling JR and Dowling TJ. “A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery”. Case Reports in Orthopedics 2018 (2018).
  6. Dimachkie MM and Barohn RJ. “Guillain-Barré syndrome and variants”. Neurology Clinic2 (2013): 491-510.
  7. Liou L-S., et al. “Epidemiology and prognostic factors of inpatient mortality of Guillain-Barré syndrome: a nationwide population study over 14 years in Asian country”. Journal of the Neurological Sciences 369 (2016): 159-164.
  8. Sejvar JJ., et al. “Guillain-Barré syndrome and Fisher syndrome: case definitions and guidelines for collection, analysis, and presentation of immunization safety data”. Vaccine3 (2011): 599.
  9. Leonhard SE., et al. “Diagnosis and management of Guillain–Barré syndrome in ten steps”. Nature Reviews Neurology11 (2019): 671-683.
  10. Sekiguchi Y., et al. “How often and when Fisher syndrome is overlapped by Guillain‐Barré syndrome or Bickerstaff brainstem encephalitis?” European Journal of Neurology 6 (2016): 1058-1063.
  11. Hiew FL., et al. “Guillain-Barré Syndrome, variants and forms fruste: Reclassification with new criteria”. Clinical Neurology and Neurosurgery 158 (2017): 114-118.
  12. Pegg EJ., et al. “An Overlapping Case of Miller Fisher Syndrome, Bickerstaff’s Encephalitis, and the ASMAN Variant of Guillain-Barre Syndrome”. Case Reports in Neurological Medicine 2016 (2016): 1596850.
  13. Wattanasit P and Sathirapanya P. “Anti-Ganglioside Antibody-Negative Miller Fisher and AMSAN Variant Guillain-Barré Overlap Syndrome”. Case Reports in Neurology1 (2020): 92-96.
  14. de Castillo LLC., et al. “A rare mimic of acute stroke: rapidly progressing Miller-Fisher Syndrome to acute motor and sensory axonal neuropathy variant of Guillain-Barre Syndrome”. BMJ Case Reports CP3 (2019): e228220.
  15. Hughes RA., et al. “Intravenous immunoglobulin for Guillain-Barré syndrome”. Cochrane Database System Review 7 (2012): Cd002063.
  16. Walgaard C., et al. “Early recognition of poor prognosis in Guillain-Barre syndrome”. Neurology11 (2011): 968-975.

Citation: Tan Chun Chau and Nik Azlan Nik Muhamad. “Miller Fisher Syndrome and Acute Motor and Sensory Axonal Neuropathy (AMSAN) Variant Guillain-Barré Overlap Syndrome (MFS/AMSAN-GBS) After Upper Respiratory Tract Infection (URTI)". Acta Scientific Clinical Case Reports 3.7 (2022): 03-09.

Copyright: © 2022 Tan Chun Chau and Nik Azlan Nik Muhamad. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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