A Comparative Study of Two-dimensional Versus Three-dimensional Strain Parameters by Acoustic Speckle Tracking Echocardiography for Assessment of Left Ventricular Systolic Function
Naeem Hasanfatta*, JC Mohan and Madhu Shukla
Department of Cardiology, Fortis Hospital Shalimar Bagh, India
*Corresponding Author: Naeem Hasanfatta, Department of Cardiology, Fortis Hospital Shalimar Bagh, India.
Received: February 23, 2022; Published: May 23, 2022
Background: Three-dimensional (3D) speckle-tracking echocardiography (3DSTE) is a recent imaging technique designed to evaluate left ventricular (LV) myocardial function and overcome potential limitations of two-dimensional (2D) echocardiographic strain analysis. The aim of this study was to evaluate the utility of 3D echocardiographic strain parameters in the assessment of global left ventricular systolic function and to study correlation between 2D and 3D strain parameters.
Methods: 2D and 3D echocardiography with STE were performed in 100 subjects (3D LVEF range, 23%–66%) who satisfied the inclusion and exclusion criteria. 3D global longitudinal strain (GLS), global circumferential strain (GCS), global radial strain (GRS), global area strain (GAS) and 2D Global longitudinal strain (GLS) were derived from grey-scale images and correlated with LV function determined by 2D and 3D echocardiographic LVEF. Values of GLS by 2DE and 3DE speckle-tracking analyses were compared. Reproducibility and time taken for the study to perform 3D STE were assessed independently.
Results: All 3D speckle-tracking echocardiographic parameters had strong correlations with 2D and 3D echocardiographic ally derived LVEF. Three-dimensional GCS was the best marker of LV function (for 2D LVEF r = -0.86, P < .0001 and 3D LVEF r = -0.87, P < 0.001). Global Area Strain (GAS) measured by 3D echocardiography showed a stronger correlation with LVEF measured by both 2D and 3D echocardiography as compared to global longitudinal strain (GLS). GLS measured by 3D echocardiography showed strong correlation with GLS measured by 2D echocardiography (r = -0.94, P < 0.001). Acquisition and analysis time for 3D STE (mean 7.04 ± 1.463 mins) was consistently faster as compared to 2D STE (Mean 11.82 ± 2.162 mins). All four 3D STE strain parameters showed good reproducibility with low inter and intra observer variability (r > 0.9, p < 0.001).
Conclusions: Global strain by 3D STE from a single 3D data set is a quick, reliable and promising novel alternative to quantitatively assess LV function and shows good correlation with LVEF obtained by 2D and 3D echo. Global longitudinal strain by 2D echocardiography correlates well with 3D global longitudinal strain. Three-dimensional STE shows good reproducibility with faster acquisition and analysis time.
Keywords: Acoustic Speckle Tracking; Three-dimensional Strain; Ejection Fraction; LV
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