Acta Scientific Clinical Case Reports

Research ArticleVolume 3 Issue 5

Role of URIC ACID in Disease: A Journey from Gout to Metabolic Syndrome

Tahseen Bilal Rather1, Gulzar Ahmad Bhat1#, Gowhar Rashid1#, Ishrat Parveiz Bhat1, Ab Nasir Sheikh1, Jaffer Wani2 and Syed Mudassar1*

1Department of Clinical Biochemistry SKIMS, Srinagar, Kashmir, India
2University of Kashmir, India
## Authors contributed equally

*Corresponding Author: Syed Mudassar, Professor and Head, Department of Clinical Biochemistry SKIMS, Srinagar, Kashmir, India.

Received: March 10, 2022; Published: April 04, 2022


Background: Uric acid (UA) is the end product of purine metabolism. Its recent link with type 2 diabetes (T2D) and COVID-19 related complications has brought this molecule to limelight. From an innocent bypasser initially thought to be associated only with gout to a central key player playing role in metabolic syndrome, uric acid has become the element of huge interest.

Aims and Objectives: The study was aimed to document the levels of serum uric acid (SUA) in general population across different age groups and gender.

Materials and Methods: A total of 858 subjects were recruited for the analysis of SUA. Samples were analysed on fully automated analyser (Beckman Coulter, AU5800). The levels were measured by uricase/POD method [1].

Results: The overall median SUA levels recorded in our population was 4.74 mg/dl (IQR = 3.61), which was within the normal reference limits. The UA levels in males were a bit higher (5 mg/dl) than females (4.5).

Conclusion: The results of our study show that serum UA levels in the study population were normal, well within the reference range. In the light of the fact that uric acid is a risk factor for many diseases, its continuous monitoring should be encouraged. 

Keywords: Metabolic Syndrome; Serum Uric Acid; Kashmir; COVID-19


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Citation: Syed Mudassar., et al. “Role of URIC ACID in Disease: A Journey from Gout to Metabolic Syndrome". Acta Scientific Clinical Case Reports 3.5 (2022): 02-04.

Copyright: © 2022 Syed Mudassar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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