Acta Scientific Clinical Case Reports

Research ArticleVolume 3 Issue 4

Maternal Depressive Disorder and Neonatal Birth Outcomes

Mohamed A Mohamed1*, Kyonna Moore2 and Hany Aly1

1Department of Neonatology, Cleveland Clinic Children’s, USA
2Newborn Services, The George Washington University Hospital, USA

*Corresponding Author: Mohamed A Mohamed, Vice Chair, Department of Neonatology, Cleveland Clinic Children’s, USA.

Received: February 22, 2022; Published: March 23, 2022

Abstract

Objective: To examine the risk of preterm birth and small for gestational age (SGA) outcomes in relation to maternal depressive disorders.

Methods: This study utilized the discharge records of 2,680,437 women who had given birth during the years of 2009, 2010, and 2011 in the U.S. Maternal depressive disorders, preterm birth, and SGA were identified using ICD9 codes. Logistic regression models were used to examine the association of maternal depressive disorders diagnosed prior to or during pregnancy with preterm birth or SGA in the offspring while controlling for several demographic, clinical and perinatal factors.

Results: Compared to women with no depressive disorders, the adjusted odds ratios (aOR) for mothers with depressive disorders to have preterm birth or SGA babies were 1.18 (CI:1.14-1.22, p < 0.001) and 1.19 (CI:1.13-1.26, p < 0.001), respectively while controlling for confounding variables. Examining the association of depressive disorders with preterm birth or SGA in different racial/ethnic groups revealed similar associations.

Conclusions: Preterm birth and SGA outcomes are increased in pregnant women with depressive disorders. Future research should focus on prompt screening of pregnant women for maternal depressive disorders and provide proper care that may modify risks of theses adverse outcomes.

Keywords: Preterm Birth; Small for Gestational Age; Adverse Birth Outcomes; Mental Illness During Pregnancy; Maternal Depressive Disorders; Maternal Depression

Bibliography

  1. “Maternal Mental Health and Child Health and Development”. WHO.int. (2014).
  2. The Center for Disease Control and Prevention. “Preterm birth” (2013).
  3. deRegnier RA. “Neurophysiologic evaluation of brain function in extremely premature newborn infants”. Seminars in Perinatology 32 (2008): 2-10.
  4. Cepeda IL., et al. “Magnetoencephalography study of brain dynamics in young children born extremely preterm”. International Congress Series 1300 (2007): 99-102.
  5. Morse SB., et al. “Early school-age outcomes of late preterm infants”. Pediatrics 123 (2009): e622-629.
  6. Anderson L., et al. “Neonatal outcome following maternal antenatal depression and anxiety: a population-based study”. American Journal Epidemiology 159 (2004): 872-881.
  7. Goedhart G. “Maternal depressive symptoms in relation to perinatal mortality and morbidity: results from a large multi-ethnic cohort study”. Perinatal Health Epidemiology in Multi-ethnic Amsterdam: Psychobiological Processes (2012): 64-79.
  8. Dayan J., et al. “Prenatal Depression, Prenatal Anxiety, and Spontaneous Preterm Birth: A prospective cohort study among women with early and regular care”. Psychosomatic Medicine 68 (2006): 938-946.
  9. Witt W., et al. “Preconception mental health predicts pregnancy complication and adverse birth outcomes: A national population-based study”. Maternal Child Health Journal7 (2012): 1525-1541.
  10. Bonari Lori., et al. “Perinatal Risks of Untreated Depression During Pregnancy”. Canadian Journal of Psychiatry 11 (2004): 726-735.
  11. “Screening for depression during and after pregnancy”. Committee Opinion No. 453. American College of Obstetricians and Gynecologists. Obstetrics and Gynecology 115 (2010): 394-395.
  12. National Institute for Healthcare Management. “Identifying and treating maternal depression: strategies and considerations for health plans”. Washington, DC: Santoro, K., Peabody, H (2010).
  13. Moore T and Pytlarz J. “Untreated Psychiatric Disorder in Pregnancy: Weighing the Risks”. Mental Health Clinic2 (2013): 100.
  14. Isaacs Maresa. Community Care Networks for Depression in Low-Income Communities and Communities of Color: A Review of the Literature. Submitted to Annie E. Casey Foundation. Washington, DC: Howard University School of Social Work and the National Alliance of Multiethnic Behavioral Health Associations (2004).
  15. Gaynes BN., et al. “Perinatal Depression: Prevalence, Screening Accuracy, and Screening Outcomes”. Rockville, MD:: Prepared by the RTI-University of North Carolina Evidence based Practice Center, under Contract No. 290-02-0016 (2005).
  16. Diego MA., et al. “Maternal psychological distress, prenatal cortisol, and fetal weight”. Psychosomatic Medicine 5 (2006): 747-753.
  17. “Health Costs and Utilization Project” (2021).
  18. Tiffany Field., et al. “Prenatal depression effects on the fetus and newborn: a review”. Infant Behavior and Development 3 (2006): 445-455.
  19. Hoffman S and Hatch M C. “Depressive symptomatology during pregnancy: Evidence for an association with decreased fetal growth in pregnancies of lower social class women”. Health Psychology6 (2000): 535-543.
  20. Grote NK., et al. “A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction”. Archives of General Psychiatry10 (2010): 1012-1024.
  21. Dunkell Schetter C and Tanner L. “Anxiety, depression, and stress in pregnancy: implications for mothers, children, research, and practice”. Current Opinion Psychiatry 25 (2012): 141-148.
  22. Dunkel Schetter C and Lobel M. “Pregnancy and birth: a multilevel analysis of stress and birth weight”. Handbook of Health Psychology 2 (2011): 427-453.
  23. Nonacs R and Cohen LS. “Depression during pregnancy: diagnosis and treatment options”. Journal of Clinical Psychiatry 7 (2002): 24-30.
  24. Rogal SS., et al. “Effects of posttraumatic stress disorder on pregnancy outcome”. Journal of Affective Disorders 102 (2007): 137-143.
  25. Rahman A., et al. “Association between antenatal depression and low birth weight in a developing country”. Acta Psychiatrica Scandinavica 115 (2007): 481-486.
  26. Michielsen L., et al. “Effects of maternal psychotropic drug dosage on birth outcomes”. Neuropsychiatric Disease and Treatment 10 (2014): 13-18.
  27. Gavin A., et al. “Maternal depressive symptoms, depression and psychiatric medication use in relation to risk of preterm delivery”. Women’s Health Issues5 (2009): 325-334.

Citation: Mohamed A Mohamed., et al. “Maternal Depressive Disorder and Neonatal Birth Outcomes". Acta Scientific Clinical Case Reports 3.4 (2022): 68-74.

Copyright: © 2022 Mohamed A Mohamed., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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