Acta Scientific Clinical Case Reports

Case ReportVolume 3 Issue 4

Primary Hypertrophic Osteoarthropathy in End Stage Renal Disease Patient with Marked Anemia. A Case Report

Tanweer Iqbal*, Ahmed Mahmoud Aborahma and Ali Mohammed Al-Lehbi

Ali Allehbi Medical Center, Riyadh, Saudi Arabia

*Corresponding Author: Tanweer Iqbal, Senior Consultant internal Medicine/Nephrology, Ali Allehbi Medical Company, Riyadh, Saudi Arabia.

Received: February 23, 2022; Published: March 10, 2022

Abstract

Primary or idiopathic hypertrophic osteoarthropathy also known as pachydermoperiostosis is a rare disease characterized by clubbing of the digits, enlargement of the extremities and synovial joint effusions and a variety of skin abnormalities resulting from cutaneous hypertrophy. Other associated features are hypertrophic gastropathy, peptic ulcer and gynecomastia. Eyelid ptosis which is caused by thickened eyelids (blepharoptosis) is a less common association with this disease. We report a rare case of a patient with a complete form of pachydermoperiostosis with bilateral ptosis, clubbing, other skin manifestations and marked erythropoietin resistant anemia.

Keywords: Primary Hypertrophic Osteoarthropathy (PHOA); Clubbing; Skin Abnormalities; Erythropoietin

Bibliography

  1. Salah BI., et al. “Complete primary pachydermoperiostosis: A case report from Jordan and review of literature”. Clinical Case Report 9 (2019): 346-352.
  2. Poormoghim H., et al. “Primary hypertrophic osteoarthropathy”. Rheumatology International 32 (2012): 607-610.
  3. Borochowitz Z and Rimoin R. “Pachydermoperiostosis”. in: Buyse ML, ed. Birth Defects Encyclopaedia. Cambridge, MA: Blackwell Scientific Publications (1990): 1349-1350. 
  4. Zanon AB., et al. “Primary hypertrophic osteoarthropathy: case report and literature review”. Brazilian Journal of Rheumatology 49 (2009): 447-455.
  5. Rastogi R and Suma GN. “Pachydermoperiostosis or primary hypertrophic osteoarthropathy: a rare clinicoradiologic case”. Indian Journal of Radiology and Imaging 2 (2009): 123-126.
  6. Martinez-Lavin M., et al. “Hypertrophic osteoarthropathy: a palindrome with a pathogenic connotation”. Current Opinion on Rheumatology 1 (2008): 88-91. 
  7. Alnimer Y., et al. “Primary idiopathic osteoarthropathy: could it be related to alcoholism?” Case Reports in Rheumatology 5 (2017): 1-4.
  8. Bergmann C., et al. “Primary hypertrophic osteoarthropathy with digital clubbing and palmoplantar hyperhidrosis caused by 15-PGHD/HPGD loss-of-function mutations”. Experimental Dermatology6 (2011): 531-533.
  9. Kumar U., et al. “Unusual associations of pachydermoperiostosis: a case report”. Indian Journal of Medical Sciences2 (2008): 65-68.
  10. Khalid A and Baqai MT. “Primary hypertrophic osteoarthropathy: a case report”. JPMA7 (2014): 843-845.

Citation: Tanweer Iqbal., et al. “Primary Hypertrophic Osteoarthropathy in End Stage Renal Disease Patient with Marked Anemia. A Case Report". Acta Scientific Clinical Case Reports 3.4 (2022): 27-29.

Copyright: © 2022 Tanweer Iqbal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US