A Combination of Mechanisms Contributes to the Development of Tardive Dyskinesia: Management Implications
Department of Psychiatry, Federal Medical Centre, Makurdi, Benue State, Nigeria
*Corresponding Author: Matthias Oyigeya, Department of Psychiatry, Federal Medical Centre, Makurdi, Benue State, Nigeria.
Received: December 01, 2021; Published: January 06, 2022
Tardive Dyskinesia (TD) has defiled all forms of therapy and continues to constitute significant clinical problem. Existing hypotheses implicate dysregulations of both excitatory and inhibitory neurotransmitters, with consequent neuronal changes/damage. The present consensus is that a combination of mechanisms contributes to the development of TD. Authors advise on a combination therapy targeted at the cellular phenomena underlying the disease.
Keywords: Tardive Dyskinesia; Hypotheses; Glutamate; Dopamine (DA)
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