Gowhar Rashid¹, Gulzar Ahmad Bhat^1,a, Aaliya Shah^2,a, Tahseen Bilal Rather^1,a, Ishrat Parvaiz¹, Sayima Farooq¹, Irfan Rashid¹ and Syed Mudassar^3*

¹Department of Clinical Biochemistry, SKIMS, Kashmir, India
²Department of Biochemistry, SKIMS Medical College, Srinagar, India
³Professor and Head, Clinical Biochemistry, SKIMS, Kashmir, India
^aContributed Equally to the Manuscript

*Corresponding Author: Syed Mudassar, Professor and Head, Clinical Biochemistry, SKIMS, Kashmir, India.

Received: December 07, 2021; Published: December 30, 2021

Abstract

Background: Amylase- an enzyme produced by the pancreas and salivary glands facilitates the breakdown of dietary starch. Many clinical manifestations are caused by abnormal blood serum amylase levels. Hence, the idea of this retrospective study was to investigate the serum amylase levels among subjects visiting the main tertiary care hospital.

Methods: A total of 1578 patients tested for different investigations including serum amylase were recruited in the Outpatient/Inpatient sections of Sher-I-Kashmir Institute of Medical Sciences (SKIMS), Srinagar for various ailments between March to November 2020.

Results: The average value documented for Serum amylase levels was 110.73 ± 85.0055 that is considered as within the acceptable limits. The average age recorded for the patients was 46.58 ± 19.73 years. There was no statistical significance between amylase levels and gender groups. However, there was a statistical significance between amylase levels and different age groups (p = 0.000).

Conclusion: There was a concordant increase of serum amylase levels with an increase in age.

Keywords: Amylase; Pancreatitis; Kashmir

Bibliography

1. Ben-Horin S., et al. “Gastroenteritis-associated hyperamylasemia: prevalence and clinical significance”. Archives of Internal Medicine6 (2002): 689-692.
2. Otsuki M., et al. “Amylase in the lung”. Cancer 4 (1977): 1656-1663.
3. Motswaledi MS., et al. “Tuberculosis alters pancreatic enzymes in the absence of pancreatitis”. African Journal of Laboratory Medicine 1 (2014): 129.
4. Gullo L., et al. “Benign pancreatic hyperenzymemia or Gullo’s syndrome”. Advances in Medical Sciences 1 (2008): 1-5.
5. T K., et al. “Amylase-producing ovarian carcinoma: A case report and a retrospective study”. Gynecologic Oncology Reports 3 (2012).
6. Guo S., et al. “Hyperamylasemia may indicate the presence of ovarian carcinoma: A case report”. Medicine (Baltimore)49 (2018): e13520.
7. Zhang J., et al. “Amylase: sensitive tumor marker for amylase-producing lung adenocarcinoma”. Journal of Thoracic Disease 4 (2013): E167-169.
8. Weitzel JN., et al. “A unique case of breast carcinoma producing pancreatic-type isoamylase”. Gastroenterology2 (1988): 519-520.
9. Rasool MT., et al. “Cancer in Kashmir, India: burden and pattern of disease”. Journal of Cancer Research and Therapeutics 2 (2012): 243-246.
10. Qurieshi MA., et al. “Gastric cancer in Kashmir”. Asian Pacific Journal of Cancer Prevention 1 (2011): 303-307.
11. Ganie MA., et al. “Prevalence of polycystic ovary syndrome (PCOS) among reproductive age women from Kashmir valley: A cross-sectional study”. International Journal of Gynecology and Obstetrics 2 (2020): 231-236.
12. Park C-H., et al. “Risk factors for malignant transformation of mature cystic teratoma. Obstetrics and Gynecology Science6 (2015): 475-480.
13. Collen MJ., et al. “Serum amylase in patients with renal insufficiency and renal failure”. American Journal of Gastroenterology 10 (1990): 1377-1380.

Citation: Syed Mudassar., et al. “Serum Amylase Levels with Respect to Different Clinical Disorders: A Hospital-based Observational Study from Kashmir". Acta Scientific Clinical Case Reports 3.1 (2022): 65-68.

Copyright: © 2022 Syed Mudassar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.