Recent Advancements in the Clinical Applications of Gold Nano-Particles
Ayan Ghorai1, Jabir Ali1, Koustav Chakraborty1, Moumita Roy1 and Arijit Bag2*
1Department of Material Science and Technology, Moulana Abul Kalam Azad University of Technology, West Bengal, India
2Department of Applied Science, Moulana Abul Kalam Azad University of Technology, West Bengal, India
*Corresponding Author: Arijit Bag, Department of Applied Science, Moulana Abul Kalam Azad University of Technology, West Bengal, India.
Received: July 01, 2021; Published: August 10, 2021
The rapid progress in the field of nanotechnology provides a variety of opportunities to improve the therapeutic strategies to fight against life-threatening diseases like cancer, HIV, COVID-19, etc. In general, higher atomic number metal nanoparticles are used for this purpose. Among a number of heavy metal nanoparticles, the gold nanoparticles of different particle sizes are more attractive due to their suitable physical and chemical properties along with excellent electromagnetic radiation absorption ability. Several disciplinary works are in progress for the last few decades to improve the applications of gold nanoparticles as biomedicine by reducing their toxicity and enhancing their efficacy.
Keywords: Gold Nanoparticle; Clinical Application; Radiotherapy; Cell Imaging; Drug Delivery; Photo Thermal Therapy
- Mesbahi Asghar. "A review on gold nanoparticles radiosensitization effect in radiation therapy of cancer”. Reports of Practical Oncology and Radiotherapy6 (2010): 176-180.
- Butterworth Karl T., et al. “Physical basis and biological mechanisms of gold nanoparticle radiosensitization”. Nanoscale16 (2012): 4830-4838.
- Xie WZ., et al. “Simulation on the molecular radiosensitization effect of gold nanoparticles in cells irradiated by x-rays”. Physics in Medicine and Biology16 (2015): 6195.
- Rippel Radoslaw A and Alexander M Seifalian. "Gold revolution—Gold nanoparticles for modern medicine and surgery”. Journal of Nanoscience and Nanotechnology5 (2011): 3740-3748.
- Nicol James R., et al. "Gold nanoparticle surface functionalization: a necessary requirement in the development of novel nanotherapeutics”. Nanomedicine 8 (2015): 1315-1326.
- Schuemann Jan., et al. “Roadmap to clinical use of gold nanoparticles for radiation sensitization”. International Journal of Radiation Oncology* Biology* Physics1 (2016): 189-205.
- Hainfeld James F.., et al. “Radiotherapy enhancement with gold nanoparticles”. Journal of Pharmacy and Pharmacology8 (2008): 977-985.
- Huang Xiaohua., et al. “Plasmonic photothermal therapy (PPTT) using gold nanoparticles”. Lasers in Medical Science3 (2008): 217-228.
- Kapoor Vibhu., et al. "An introduction to PET-CT imaging”. Radiographics 2 (2004): 523-543.
- Langer Robert. "Drug delivery and targeting”. Nature6679 Suppl (1998): 5-10.
- Li Jinfeng., et al. “Photo-induced tumor therapy using MnO2/IrO2-PVP nano-enzyme with TME-responsive behaviors”. Colloids and Surfaces B: Biointerfaces 205 (2021): 111852.
- Chen Helen HW and Macus Tien Kuo. "Improving radiotherapy in cancer treatment: Promises and challenges”. Oncotarget 37 (2017): 62742.
- Wang Yifan., et al. “Combining immunotherapy and radiotherapy for cancer treatment: current challenges and future directions”. Frontiers in Pharmacology 9 (2018): 185.
- Qi Fanghua., et al. “Chinese herbal medicines as adjuvant treatment during chemo or radio-therapy for cancer”. Bioscience Trends6 (2010).
- Yaromina Ala., et al. "Individualization of cancer treatment from radiotherapy perspective”. Molecular Oncology 2 (2012): 211-221.
- Vicini Frank A.., et al. “Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy”. International Journal of Radiation Oncology* Biology* Physics5 (2002): 1336-1344.
- Barton Michael B., et al. "Role of radiotherapy in cancer control in low-income and middle-income countries”. The Lancet Oncology7 (2006): 584-595.
- Stauffer PR and S Nahum Goldberg. "Introduction: thermal ablation therapy”. International Journal of Hyperthermia7 (2004): 671-677.
- Chu Katrina F and Damian E Dupuy. "Thermal ablation of tumours: biological mechanisms and advances in therapy”. Nature Reviews Cancer3 (2014): 199-208.
- Roessl E and R Proksa. "K-edge imaging in x-ray computed tomography using multi-bin photon counting detectors”. Physics in Medicine and Biology15 (2007): 4679.
- Ghadiri H., et al. “K-edge ratio method for identification of multiple nanoparticulate contrast agents by spectral CT imaging”. The British Journal of Radiology1029 (2013): 20130308.
- Roa Wilson., et al. “Pharmacokinetic and toxicological evaluation of multi-functional thiol-6-fluoro-6-deoxy-D-glucose gold nanoparticles in vivo”. Nanotechnology37 (2012): 375101.
- Kaushik Nagendra Kumar., et al. “Low doses of PEG-coated gold nanoparticles sensitize solid tumors to cold plasma by blocking the PI3K/AKT-driven signaling axis to suppress cellular transformation by inhibiting growth and EMT”. Biomaterials 87 (2016): 118-130.
- Apaolaza PS., et al. “Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution”. Experimental Eye Research 198 (2020): 108151.
- Fogh Shannon E., et al. “Hypofractionated stereotactic radiation therapy: an effective therapy for recurrent high-grade gliomas”. Journal of Clinical Oncology18 (2010): 3048.
- Xie Jiani., et al. “Emerging strategies of nanomaterial‐mediated tumor radiosensitization”. Advanced Materials3 (2019): 1802244.
- Claudio Cabral-Romero and Shankararaman Chellam. "Bismuth nanoparticles: antimicrobials of broad-spectrum, low cost and safety”. Nanomedicine (2014): 430-437.
- Guan Zeyi., et al. “Novel zinc/tungsten carbide nanocomposite as bioabsorbable implant”. Materials Letters 263 (2020): 127282.
- Koshevaya Ekaterina D., et al. "Tantalum oxide nanoparticles as an advanced platform for cancer diagnostics: a review and perspective”. Journal of Materials Chemistry B (2021).
- Bonvalot Sylvie., et al. “NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act. In. Sarc): a multicentre, phase 2–3, randomised, controlled trial”. The Lancet Oncology8 (2019): 1148-1159.
- Foulkes Rachel., et al. “Silver-nanoparticle-mediated therapies in the treatment of pancreatic cancer”. ACS Applied Nano Materials4 (2019): 1758-1772.
- Kujawa Joanna., et al. “Crystalline porous frameworks as nano-enhancers for membrane liquid separation–Recent developments”. Coordination Chemistry Reviews 440 (2021): 213969.
- Chen Yao., et al. “Gold Nanoparticles as Radiosensitizers in Cancer Radiotherapy”. International Journal of Nanomedicine 15 (2020): 9407.
- Kumar Vineet., et al. “Gold nanoparticle exposure induces growth and yield enhancement in Arabidopsis thaliana”. Science of the Total Environment 461 (2013): 462-468.
- Yasui Hironobu., et al. “Radiosensitization of tumor cells through endoplasmic reticulum stress induced by PEGylated nanogel containing gold nanoparticles”. Cancer Letters1 (2014): 151-158.