COVID-19 and Black Fungus: New Insights Explaining the Pathogenicity of the Disease
Ahed J Alkhatib1,2*
1Department of Legal Medicine, Toxicology and Forensic Medicine, Jordan University of Science and Technology, Jordan
2International Mariinskaya Academy, Department of Medicine and Critical Care, Department of Philosophy, Academician Secretary of Department of Sociology, Jordan
*Corresponding Author: Ahed J Alkhatib, Department of Legal Medicine, Toxicology and Forensic Medicine, Jordan University of Science and Technology, Jordan.
Received: June 30, 2021; Published: July 21, 2021
The latest outbreak of COVID-19 has been associated with black fungus. In this study, the author reviewed the literature regarding the black fungus and its coexistence with COVID-19. Literature indicated several risk factors such as being diabetic and immunocompromised. We added our new insights to the pathogenesis of fungi through the results of our previous studies in which we demonstrated that fungi express estrogen receptor, BCL2 protein, and p53. These biomarkers imply that fungi benefit from the microenvironment if estrogen exists. However, if patients under steroid treatments, they are likely to develop secondary infections such as black fungus.
Keywords: Black Fungus; COVID-19; p53; BCL2; Estrogen Receptor
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