Anusha Yanamadala* and Parikshit Thakur Hameer
Presbyterian Plains Regional Medical Center; Clovis, NM, USA
*Corresponding Author: Anusha Yanamadala, Presbyterian Plains Regional Medical Center; Clovis, NM, USA.
Received: April 15, 2021; Published: June 02, 2021
Citation: Anusha Yanamadala and Parikshit Thakur Hameer. “A Good History Can Unlock Puzzle- A Case Report of Ibuprofen Induced Minimal Change Glomerulonephritis". Acta Scientific Clinical Case Reports 2.7 (2021): 21-22.
Minimal-change disease (MCD) is uncommon in adults contributing about 10% of nephrotic syndrome cases in adults. Underlying pathology is thought to be due to T-cell or B- cell dysfunction resulting in circulating factors like IL-13 affecting glomerular capillary wall permeability resulting in significant proteinuria. NSAIDs (Nonsteroidal anti-inflammatory drugs) are common cause for secondary MCD but often underdiagnosed with missing information from history. Untreated MCD were associated with a high risk for thromboembolism and mortality. We are presenting a case report of ibuprofen induced minimal change glomerulonephritis in a young patient who took ibuprofen on a regular basis with a history of fracture for pain management without subsequent monitoring and unaware of significant side effects of medication.
Keywords: Ibuprofen; Glomerulonephritis; Minimal-Change Disease (MCD)
Copyright: © 2021 Anusha Yanamadala and Parikshit Thakur Hameer. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.