Anubha Bajaj*

Department of Histopathology, Panjab University/A.B. Diagnostics, India

*Corresponding Author: Anubha Bajaj, Department of Histopathology, Panjab University/A.B. Diagnostics, India.

Received: August 02, 2023; Published: September 01, 2023

Superficial CD34+ fibroblastic tumour is a distinctive, low grade tumefaction arising within superficial sites as diverse cutaneous surfaces or subcutaneous tissue. Superficial CD34+ fibroblastic tumour is additionally designated as PRDM10 rearranged soft tissue tumour. Characteristically, fascicular proliferation of spindle shaped cells pervaded with abundant, eosinophilic, granular to glassy cytoplasm is encountered. Although nuclear pleomorphism may be significant, mitotic activity is minimal. Tumour cells comprehensively appear immune reactive to CD34. Besides, focal immune reactivity to keratin (AE1/AE3) is encountered within ~ 70% neoplasms.

References

1. Sugita S., et al. “Usefulness of SynCAM3 and cyclin D1 immunohistochemistry in distinguishing superficial CD34-positive fibroblastic tumor from its histological mimics”. Medical Molecular Morphology 1 (2023): 69-77.
2. Salah HT., et al. “Superficial CD34-positive fibroblastic tumor (SCPFT): A review of pathological and clinical features”. Annals of Diagnostic Pathology 58 (2022): 151937.
3. Anderson WJ., et al. “Superficial CD34-Positive Fibroblastic Tumor: A Clinicopathologic, Immunohistochemical, and Molecular Study of 59 Cases”. The American Journal of Surgical Pathology 10 (2022): 1329-1339. 
4. Bruce-Brand C., et al. “Superficial CD34 Positive Fibroblastic Tumour with Myxoid Stroma”. International Journal of Surgical Pathology 11 (2022): 10668969221126109.
5. Salah HT., et al. “Case of recurrent superficial CD34-positive fibroblastic tumor”. Journal of Cutaneous Pathology (2022).
6. Image 1 Courtesy: Wiley online library.
7. Image 2 Courtesy: Nature.com.

Citation

Citation: Anubha Bajaj. “Ostensible and Wiry-Superficial CD34+ Fibroblastic Tumour." Acta Scientific Cancer Biology 7.8 (2023): 01-03.

Copyright

Copyright: © 2023 Anubha Bajaj. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.