Seema Devi¹*, Rajesh Kumar Singh², Abhishek Kumar³, Raina Rana⁴ and Amsan Prakah⁵

¹Additional Professor, Department of Radiation Oncology, IGIMS, Patna, India
²Professor, Department of Radiation Oncology, IGIMS, Patna, India
³PG 3^rd Year, Department of Radiation Oncology, IGIMS, Patna, India
⁴PG 2^nd Year, Department of Radiation Oncology, IGIMS, Patna, India
⁵Statistian, IGIMS, Patna, India

*Corresponding Author: Seema Devi, Additional Professor, Department of Radiation Oncology, IGIMS, Patna, India.

Received: June 22, 2023; Published: June 30, 2023

Abstract

Background: Globally 85% of Paediatrics Cancer is reported in developing world. In India nearly 45,000 new paediatrics cancer cases are reported every year which contributed less than 5% of all the cancer cases (1) Riberto 5-year survival rate reported is only 10%, Globally more than 0.2 million cases are diagnosed every year. In developed world 5-year survival rate is quite high about 95% (2) Steller Average incidence of 75 to 150 Paediatrics cancer per million children, Average incidence in India is higher as compared to western population.

Material and Method: Our center is the State Cancer Institute, Indira Gandhi Institute of Medical Science, Patna which caters approximately million population of Bihar. All the pediatric patients 0–14-year male registered under HBCR program in Department of Radiation Oncology.

Result: Total 1978 childhood cancer was reported in our study. In which 357(68.3%) were male children and 627 (32.48%) where female children 0-19 years age groups common age group was 5 to 19 years 1058(78.31%) cases reported with this age group while 293 cases were reported in 0-4 years in male children which in girl children most cancer age group was 10-19 years in which 358 (57.09%) patients were reported.

 Keywords: Childhood Cancer; Pediatric Cancer

References

1. Ribeiro RC., et al. “Baseline status of pediatric oncology care in 10 low income or mid-income countries receiving My Child Matters support: a descriptive study”. Lancet 9 (2008): 721-729.
2. Stiller CA and Parkin DM. “Geographic and ethnic variations in the incidence of childhood cancer”. British Medical Bulletin 52 (1996): 682-703.
3. Parkin DM., et al. “The international incidence of childhood cancer”. International Journal of Cancer 42 (1988): 511-520.
4. Barr R., et al. “Pediatric Oncology in Countries with Limited Resources”. In: Pizzo PA,Poplack DG, eds. Principles and Practice of Pediatric Oncology, 5^th Philadelphia: Lippincott Williams and Wilkins (2006): 1605-17
5. NCRP (2021).
6. Steliarova-Foucher E., et al. “International incidence of childhood cancer 2001-10: A population-based registry study”. Lancet Oncology 18 (2017): 719-731.
7. Gupta S., et al. “Treating childhood cancer in low-and middle-income countries”. In: Gelband H, Jha P, Sankaranarayanan R, et al. editors cancer: Disease control priorities, Volume 3. The International Bank for Reconstruction and Development world Bank; 2015 Chapter 7.
8. World Health Organisation. CANCER Today International agency for research on cancer (2020).
9. Xie L., et al. “Childhood cancer incidence in Canada: Demographical and geographic variation of temporal trend (1992-2010)”. Health Promotion and Chronic Disease Prevention in Canada 38 (2018): 79-113.
10. Baade PD., et al. “Trends in incidence of childhood cancer in Australia, 1983-2006”. British Journal of Cancer 102 (2010): 620-626.
11. Liu YL., et al. “Incidence of cancer in childhood aged 0-14 years in Taiwan 1996-2010”. Cancer Epidemiology 39 (2015): 21-28.
12. Das S., et al. “Childhood cancer incidence in India between 2012 and 2014: Report of a population based cancer registry.” Indian Pediatrics 54 (2017): 1033-1036.
13. Swaminathan R., et al. “Childhood cancers in Chennai, India, 1990-2001: Incidence and survival”. International Journal of Cancer 122 (2008): 2607-2611.
14. Stiller C editor. “Childhood cancer in Britain: Incidence survival, mortality”. Oxford; Oxford University Press (2007).
15. Gurney JG and Bondy ML. “Epidemiology of childhood cancer”. In: Pizzo PA, Poplack Philadelphia; Lippincott Williams and Wikins (2006): 2-14.
16. Vatsna Rathore., et al. “Delivery of Services to Childhood Cancer Survivors in India: A National”. Indian Journal of Medical and Paediatric Oncology5 (2020): 707.
17. Arora RS., et al. “Epidemiology of childhood cancer in India”. Indian Journal of Cancer4 (2009): 264-273.
18. Amare P., et al. “Clinical significance of cytogenetic findings at diagnosis and in remission in childhood and adult acute lymphoblastic leukemia: experience from India”. Cancer Genetics and Cytogenetics 110 (1999): 44-53.
19. Magrath I., et al. “Treatment of acute lymphoblastic leukaemia in countries with limited resources; lessons from use of a single protocol in India over a twenty-year period”. European Journal of Cancer 41 (2005): 1570-1583.
20. Rajalekshmy KR., et al. “Immunophenotyping of acute lymphoblastic leukaemia in Madras, India”. Leukemia Research 18 (1994): 183-190.
21. Siraj AK., et al. “Frequencies of the major subgroups of precursor B-cell acute lymphoblastic leukemia in Indian children differ from the West”. Leukemia 17 (2003): 1192-1193.
22. Amare R., et al. “Acute leukemia in children: a review of the current Indian data”. South Asian Journal of Cancer 5 (2016): 155.
23. DA Slegel., et al. “Rates and trends of pediatric acute lymphoblastic leukemia- united States, 2001-2014”. MMWR 66 (2017) 950-954.
24. MA Smith., et al. “Declining childhood and adolescent cancer mortality: Childhood and Adolescent Cancer Mortality”. Cancer 120 (2014) 2497-2506.
25. R Arora., et al. “Epidemiology of childhood cancer In India”. Indian Journal of Cancer 46 (2009): 264.
26. Ramot B and Magrath I. “Hypothesis: The environment is major determinant of the immunological sub-type of lymphoma and acute lymphoblastic leukaemia in children”. British Journal of Haematology 50 (1982): 183-189.
27. V Radhakrishnan., et al. “Pediatric nonblastic non-hodgkins’s lymphoma: a perspective from India”. Indian Journal of Medical and Paediatric Oncology 39 (2018): 13.
28. A Patel., et al. “Poor performance status, urban residence and female sex predict inferior survival in pediatric advanced stage mature B-NHL. In an Indian tertiary care center”. Pediatric Hematology and Oncology 35 (2018): 23-32.
29. A Mukhopadhyay., et al. “Result of paediatric non Hodgkin’s lymphoma with intensified short duration chemotherapy : a result from eastern India”. Blood11 (2008): 4952.
30. A Patel., et al. “Outcome of early stage pediatric non-lymphoblastic non-hodgkin lymphoma”. Indian Journal of Pediatrics 85 (2018): 782-784.
31. LS Arya., et al. “Hodgkin’s disease in Indian children: outcome with chemotherapy alone”. Pediatric Blood Cancer 46 (2006) 26-34.
32. Cancer Statistics Review, 1975-2016 - SEER Statistics (2016).
33. V Radhakrishnan., et al. “Pediatric Hodgkin lymphoma treated at Cancer Institute, Chennai, India: long-term outcome”. Journal of Global Oncology 3 (2017) 545-554.
34. Consolidated Report of Hospital Based Cancer Registries: 2012-2014 (2019).
35. C Sarkar., et al. “Spectrum of pediatric brain tumors in …..”.
36. R Madhavan., et al. “Pediatric brain tumors: an analysis of 5 years of data from a tertiary cancer care center, India”. Indian Journal of Cancer 53 (2016): 562.
37. Black WC. “Increasing incidence of childhood primary malignant brain tumors—enigma or no-brainer?” Journal of the National Cancer Institute 90 (1998): 1249-1251.
38. R Swaminathan., et al. “Childhood cancers in Chennai, India, 1990-2001: Incidence and survival”. International Journal of Cancer 122 (2008) 2607-2611.
39. Tyagi BB., et al. “Childhood Cancer Incidence in Delhi, 1996-2000”. Indian Journal of Medical and Paediatric Oncology 27 (2006): 13-18.
40. Swaminathan R., et al. “Childhood cancers in Chennai, India, 1990-2001: incidence and survival”. International Journal of Cancer 122 (2008): 2607-2611.
41. A Nandakumar., et al. “Descriptive epidemiology of childhood cancers in Bangalore, India”. Cancer Causes Control 7 (1996) 405-410.
42. B Biswas., et al. “Developing a prognostic model for localized Ewing sarcoma family of tumors: a single institutional experience of 224 cases treated with uniform chemotherapy protocol: localized Ewing's Sarcoa”. Journal of Surgical Oncology 111 (2015): 683-689.
43. B Biswas., et al. “Hypoalbuminaemia is an independent predictor of poor outcome in metastatic ewing's sarcoma family of tumours: a single institutional experience of 150 cases treated with uniform chemotherapy protocol”. Clinical Oncology 26 (2014) 722-729.
44. V Nataraj., et al. “Developing a prognostic model for patients with localized osteosarcoma treated with uniform chemotherapy protocol without high dose methotrexate: a Single center experience of 237 patients: prognostic model in Localized Osteosarcoma”. Journal of Surgical Oncology 112 (2015): 662-668.
45. R Sukumaran., et al. “Methotrexate free Chemotherapy and limb salvage surgery for paediatric osteosarcoma in India”. Indian Journal of Orthopaedics 52 (2018) 58.
46. RS Iyer., et al. “Ewing's Sarcoma”. Journal of Surgical Oncology 52 (1993) 188-192.
47. S H Advani., et al. “Adjuvant Chemotherapy in Ewing's Sarcoma”. Journal of Surgical Oncology 32 (1986): 76-78.
48. S Kaliki., et al. “RETINOBLASTOMA IN INDIA: Clinical presentation and outcome in 1457 patients (2074 eyes)”. Retina 39 (2019): 379-391.
49. VP Reddy., et al. “Demographics, Clinical profile, Management, and outcome of retinoblastoma in a tertiary care center in southern India”. Journal of Clinical Oncology 25 (2007): 20011-20011.
50. SK Gupta., et al. “Survival and outcome of retinoblastoma treated by neo-adjuvant chemotherapy in India”. Cancer Report 2 (2019).
51. Pandey MM., et al. “Population dynamics in India”. International Journal of Scientific and Engineering Research 6 (2015): 2106-2133.
52. Kaatsch P. “Epidemiology of childhood cancer”. Cancer Treatment Reviews 36 (2010): 277-284.
53. Eden T. “Aetiology of childhood leukaemia”. Cancer Treatment Reviews 36 (2010): 286-297.
54. Johnson KJ., et al. “Paternal age and risk of childhood cancer: A pooled analysis”. Epidemiology 20 (2009): 475-483.
55. Three Year Report of PBCR 2012-2014 (2019).
56. Three Year Report of the Population Based Cancer Registries 2009-2011: Report of 25 PBCRs. National Cancer Registry Programme. Indian Council Medical Research, Banglore (2013).
57. Ganguly S., et al. “Childhood cancer in India”. Cancer Epidemiology 71 (2021): 101679.
58. Khanna R and Verma SK. “Pediatric hepatocellular carcinoma”. World Journal of Gastroenterology35 (2018): 3980-99.
59. Chen WJ., et al. “Primary malignant tumor of liver in infants and children in Taiwan”. The Journal of Pediatric Surgery5 (1988): 457-461.
60. Chan KL., et al. “Paediatric hepatoblastoma and hepatocellular”.
61. Blumer SL., et al. “Sporadie adenocarcinoma of the colon in children: Case series and review of the literature”. Journal of Pediatric Hematology/Oncology 34 (2012): e137-141.
62. Three-Year Report of the Population Based Cancer Registries-2009-2011. National Cancer Registry Programme. Banglore, India: India Council of Medical Research (ICMR) (2013).
63. Hartman GE and Shochat SJ. “Primary pulmonary neoplasms of childhood: a review”. The Annals of Thoracic Surgery 36 (1983): 108-119.
64. Harting MT., et al. “Treatment issues in pediatric gastric adenocarcinoma”. The Journal of Pediatric Surgery8 (2004): e8-10.
65. Simmons P S., et al. “Breast carcinoma in young women”. Obstetrics and Gynecology3 (2011): 529-536.
66. Shannon C and Smith I E. “Breast cancer in adolescents and young women”. European Journal of Cancer18 (2003): 2632-2642.
67. Murphy J J., et al. “Breast cancer in a 6-year-old child”. The Journal of Pediatric Surgery5 (2000): 765-767.
68. Wohlmuth C and Wohlmuth-Wieser I. “Gynecologic Malignancies in Children and Adolescents: How Common is the Uncommon?” Journal of Clinical Medicine4 (2021): 722.
69. Smith RJ and Robinson RA. “Head and neck malignancies”. In: Cummings CW, editor. In Pediatric otolaryngology head and neck surgery. Mosby: St. Louis (1998): 229-247.

Citation

Citation: Seema Devi., et al. “Common Trend of Childhood Cancer in Eastern India" Acta Scientific Cancer Biology 7.5 (2023): 23-33.

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Copyright: © 2023 Seema Devi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.