Seema Devi1*, Abhishek Kumar2 and P Minakshi3
1Additional Professor, Department of Radiation Oncology, IGIMS, Patna, India
2PG 3rd Year, Department of Radiation Oncology, IGIMS, Patna, India
3PG 1st Year, Department of Radiation Oncology, IGIMS, Patna, India
*Corresponding Author: Seema Devi, Additional Professor, Department of Radiation Oncology, IGIMS, Patna, India.
Received: March 24, 2023; Published: March 28, 2023
Melanoma develops from pigment containing cells. Melanocytes commonly occurs in skin. Commonly it occurs on the legs in females and on the back in the males . Melanoma of anorectum is a rare disease constitutes only 0.5% to 4% of the all malignancies of anorectal malignancies with very poor prognosis, 10 to 19 months after surgical operations. A 32-year female presented with chief complaint of continuous rectal bleeding for last 1 year. Colonoscopy shown sessile growth extending from 8 to 12 O’clock with irregular surface 2cm from anal verge, seen up to caecum. All melanoma originates from derivative of neural crest, During foetal development melanocytes migrated in different sites of the body like skin, retina, uveal tract and mucosal surface [4,5]. 90% of melanoma are cutaneous melanoma. Many studies recommended systematic chemotherapy and radiation. Chemotherapy agents like cisplatin, vinblastine, dacarbazine. Interferon alpha and interleukin 2 are shown efficacy against melanoma  Ano Rectal melanoma is a rare disease and having poor prognosis. Patient may ignore the symptoms as having haemorrhoids, fistula due to symptoms like bleeding per rectum, pain during defecation. Biopsy should be followed by Immunohistochemistry examination for confirmation of diagnosis. Surgical approach, radiotherapy, chemotherapy can be considered depending on extent of the disease.
Keywords: Anorectum; Melanoma; Melanocytes
Citation: Seema Devi., et al. “Malignant Melanoma of AnoRectum" Acta Scientific Cancer Biology 7.2 (2023): 11-14.
Copyright: © 2023 Seema Devi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.