Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Clinical Review Volume 7 Issue 1

Gyration and Curlicue-Sézary Syndrome

Anubha Bajaj*

Consultant, Histopathologist, A.B. Diagnostics, India

*Corresponding Author: Anubha Bajaj, Consultant, Histopathologist, A.B. Diagnostics, India.

Received: December 13, 2022; Published: February 24, 2023

Erythrodermic cutaneous T cell lymphoma (CTCL) is constituted of primary cutaneous lymphomas which manifest erythroderma such as Sézary syndrome and erythrodermic mycosis fungoides.

Sézary syndrome is defined as a leukemic variant of cutaneous T cell lymphoma (CTCL) demonstrating erythroderma, generalized lymphadenopathy and clonal T cell proliferation. Clonal, neoplastic T cells are imbued with cerebriform nuclei (Sézary cells) and may disseminate within cutaneous surfaces, regional lymph nodes and peripheral blood.


  1. Roccuzzo G., et al. “Sézary Syndrome: Different Erythroderma Morphological Features with Proposal for a Clinical Score System”. Cells3 (2022): 333.
  2. Jonak C., et al. “Mycosis fungoides and Sézary syndrome”. Journal der Deutschen Dermatologischen Gesellschaft 9 (2021): 1307-1334.
  3. Vakiti A., et al. “Sézary Syndrome”. Stat Pearls International 2022, Treasure Island, Florida (20202).
  4. Snowden C., et al. “Partial remission of advanced untreated Sézary syndrome after COVID-19”. JAAD Case Report 21 (2022): 165-168.
  5. Image 1 Courtesy: Plastic surgery key.
  6. Image 2 Courtesy: Springer link.


Citation: Anubha Bajaj. “Gyration and Curlicue-Sézary Syndrome" Acta Scientific Cancer Biology 7.1 (2023): 15-19.


Copyright: © 2022 Anubha Bajaj. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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