Zeenat Ara¹, Sandeep Pandey²,Shatakshi Pant¹, Ramesh mani Tripathi² and Shahwaliullah¹*

¹Department of Orthopaedic Surgery, King George’s Medical University, Lucknow
²Department of Biochemistry King George's Medical University, Lucknow

*Corresponding Author: Shah Walliullah,Department of Orthopaedic Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Received: August 21, 2022; Published: September 30, 2022

Abstract

Following lymphomas and brain malignancies, osteosarcomas are the most prevalent primary bone tumours in children and adolescents. The development of osteoid, or immature bone, by malignant mesenchymal cells serves as its defining characteristic. However the cause of the OS is still unknown, however in children, the disease appears to be sporadic. Genetics also plays major role in OS, thus This article examines the origin, clinical manifestation, diagnostic procedures, and treatment of osteosarcoma. Adjuvant chemotherapy was introduced in the 1970s, increasing patient 10-year survival from 30% to around 50% as a result of tumour excision. The first step to enhancing these figures is a greater comprehension of this illness.

Keywords: Osteosarcomas; Pagets Disease; Malignant Mesenchymal Cells; Tumour; Osteoid; Limb Salvage; Osteoblast, Plain Radiograph; Computed Tomography; MRI; MFH (Malignant Fibrous Histiocytoma)

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Citation

Citation: Shah Walliullah., et al. “An Update on Osteosarcoma" Acta Scientific Cancer Biology 6.6 (2022): 26-39.

Copyright

Copyright: © 2022 Shah Walliullah., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.