Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Research Article Volume 6 Issue 6

Theranostics as a Management Oral Cancer - A Ray of Hope

Mahesh KP*

Associate Professor, Department of Oral Medicine and Radiology, JSS Dental College and Hospital, JSSAHER, Mysore, India

*Corresponding Author: Mahesh KP, Associate Professor, Department of Oral Medicine and Radiology, JSS Dental College and Hospital, JSSAHER, Mysore, India.

Received: September 12, 2022; Published: September 20, 2022


Nanotheranostics is a multimodal platform that comprises a combination of a therapeutic agent, an imaging agent (photosensitized nanoparticle), and a ligand or carrier molecule. This serves as both therapy and diagnosis for cancer treatments. Due to the distinctive nature of the tumor microenvironment, nanoparticle-based drug delivery systems have the added advantage of enhanced permeation retention. The conjugation of metal nanoparticles such as gold and titanium dioxide is promising as they have unique properties for cancer bioimaging and hyperthermia-based treatments. The conventional treatment modalities of cancer have limitations concerning high radiation and lack of specificity spanning to extensive side effects. In orofacial cancer, conventional treatments require surgical intervention due to late diagnosis leading to facial disfigurement, eating, and speech disability. Included in the approach is to target the cancer cells using a combination of photothermal and photodynamic therapy to develop a non-invasive technique.

Keywords: Oral Oncology; Nanotechnology; Nanotheranostics; Nanoparticles; Tumour


  1. Mahesh KP. “Nanotheranostics- novel modality for integrating diagnosis and therapy for oral cancer”. Acta Scientific Dental Sciences9 (2018).
  2. Alessandro Parodi., et al. “Smart Nanotheranostics Responsive to Pathological”. Frontiers in Bioengeenering and Biotechnology (2020).
  3. S Jeelani., et al. “Theranostics: A treasured tailor for tomorrow”. Journal of Pharmacy and Bioallied Sciences 1 (2014): S6-S8.
  4. Pene F., et al. “Toward theragnostics”. Critical Care Medicine 37 (2009): S50-58.
  5. Hassan Dana., et al. “Molecular Mechanisms and Biological Functions of siRNA”. International Journal of Biomedical Science 2 (2017): 48-57.
  6. Danielle Glick., et al. “Autophagy: cellular and molecular mechanisms”. The Journal of Pathology 1 (2010): 3-12.
  7. Bhattarai N and Bhattarai SR. “Theranostic nanoparticles: A recent breakthrough in nanotechnology”. Journal of Nanomedicine and Nanotechnology 3 (2012): e114.
  8. Mohd yofout., et al. “Gold nanoparticles as a drug delivery system for standard chemotherapeutics: A new lead for targeted pharmacological cancer treatments”. Scientific African 11 (2021).
  9. Patrizia Agostinis., et al. “PHOTODYNAMIC THERAPY OF CANCER: AN UPDATE”. CA: A Cancer Journal for Clinicians4 (2021): 250-281.
  10. Zohara Yusaf., et al. “The application of titanium dioxide, zinc oxide, fullerene, and graphene nanoparticles in photodynamic therapy”. Cancer Nanotheranostics1 (2017).
  11. Minhuhan Lan., et al. “Photosensitizers for Photodynamic Therapy”. Advanced Healthcare Materials 13 (2019): e1900132.
  12. Emillano schena., et al. “Laser Ablation for Cancer: Past, Present and Future”. Journal of Functional Biomaterials 2 (2017): 19.
  13. Jarmo T Alander., et al. “A Review of Indocyanine Green”. Fluorescent Imaging in Surgery (2012).


Citation: Mahesh KP. “Theranostics as a Management Oral Cancer - A Ray of Hope." Acta Scientific Cancer Biology 6.6 (2022): 16-18.


Copyright: © 2022 Mahesh KP. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.183

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