Despite Gardasil 9 Success Not Reached in Complete Eradication of High Risk Human Papilloma Virus - What is the Next Step For Cervical, Oropharyngeal Cancers Prevention
Kulvinder Kochar Kaur*
Scientific Director, Dr Kulvinder Kaur Centre for Human Reproduction, Jalandhar, Punjab, India
*Corresponding Author: Kulvinder Kochar Kaur, Scientific Director, Dr Kulvinder Kaur Centre for Human Reproduction, Jalandhar, Punjab, India.
Received:
January 31, 2020; Published: February 10, 2022
We reviewed earlier the importance of human papilloma virus (HPV), in Cervical Cancer development with role of various viral proteins, as well as oropharyngeal cancer [1,2]. Although 90% of HPV infections get cleared within 2 yrs without need for medical treatment, persistent infections with HPV’s at high risk (HR- HPV’s) can progress to cancer. Low risk HPV (LR HPV) usually don’t cause cancers but get correlated with genital warts as well as respiratory papillomatosis [3,4]. Besides that other proof correlated HPV with vaginal, vulvar penile, anal along with oropharyngeal Cancer particularly tonsillar, as well as base of tongue [4].
References
- Chang CT., et al. “Mixed Sequence Reader: A Program for Analyzing DNA Sequences with Heterozygous Base Calling”. The Scientific World Journal 10 (2012).
- Aswini YB and Varun S. “Genetics in public health: Rarely explored”. Indian Journal of Human Genetics 16 (2010): 47-54.
- Korf BR. “Genetics in medical practice”. Genetics in Medicine 4 (2002): 10S.
- Kardia SL., et al. “Family-centered approaches to understanding and preventing coronary heart disease”. American Journal of Preventive Medicine 24 (2003): 143-151.
- Khoury MJ. “Genetics and genomics in practice: The continuum from genetic disease to genetic information in health and disease”. Genetics in Medicine 5 (2003): 261.
- Mahdieh N., et al. “Heterozygosity and allele frequencies of the two VNTRs (ApoB and D1S80) in Iranian population”. Indian Journal of Human Genetics 11 (2005): 31-34.
- Mahdieh N and Rabbani B. "An overview of mutation detection methods in genetic disorders”. Iranian Journal of Pediatric 23 (2013): 375-388.
- Marengo-Rowe AJ. “The thalassemias and related disorders”. Proc (Bayl Univ Med Cent) 20 (2007): 27-31.
- Shakeel M., et al. “Investigation of molecular heterogeneity of beta-thalassemia disorder in District Charsadda of Pakistan”. Pakistan Journal of Medical Sciences 32 (2016): 491-494.
- Galanello R and Cao A. “Alpha-thalassemia”. Genetics in Medicine 13 (2011): 83.
- Yasmeen H., et al. “The molecular characterization of Beta globin gene in thalassemia patients reveals rare and a novel mutations in Pakistani population”. European Journal of Medical Genetics 8 (2016): 355-362.
- Ansari SH., et al. “Molecular epidemiology of βthalassemia in Pakistan: Far reaching implications”. Indian Journal of Human Genetics 18 (2012): 193-197.
- Chial H. “DNA sequencing technologies; key to the Human Genome Project”. Nature Education 1 (2008): 219.
Citation
Copyright