A Review on Role of Red Wine Polyphenols in Cancer Treatment
Department of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, India
*Corresponding Author: Shiuli Guchait, Department of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, India.
January 27, 2022; Published: February 07, 2022
This paper presents an overview of the role of red wine polyphenols in cancer treatments. Nowadays one of the deadliest diseases in the world is cancer. According to the World Health Organization, cancer is known to be the second leading cause of death across the world. The most common cancer treatment plans are either surgery, radiation therapy or chemotherapy. But these conventional cancer therapies result in serious adverse effects in humans. A recent study shows that an antioxidant found in grape skins and seeds, known as resveratrol, a part of a group of phenolic compounds called polyphenol. Grape polyphenols are used for preventing diseases caused due to oxidative stress. It prevents cancer cells from replicating and spreading inside and enhances the effectiveness of radiation and chemotherapy cancer treatments. Various phytochemicals found in wine such as lignans, quercetin, and resveratrol have estrogenic properties. Animal research suggests that they synergistically change the gene expression in cancer cells to inhibit their growth and colony formation and thus reduce the incidence of cancer.
Keywords: Red Wine; Cancers; Polyphenols; Resveratrol; Phenolic Compounds; Antioxidants; Phytochemicals
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