Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Case Report Volume 5 Issue 10

Anesthetic Management of a Patient with Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Symptoms (MELAS): A Case Report

Refaat Shehab1* and MO Ababneh2

1Senior Consultant, Anaesthesiologist, Abdali Medical Centre, Al-Istethmar Street - Abdali Boulevard - Amman, Jordan
2Consultant, Clinical Director, Anaesthesia Department, Abdali Medical Centre, Al-Istethmar Street - Abdali Boulevard - Amman, Jordan

*Corresponding Author: Refaat Shehab, Senior Consultant, Anaesthesiologist, Abdali Medical Centre, Al-Istethmar Street - Abdali Boulevard - Amman, Jordan.

Received: August 27, 2021; Published:

Abstract

Mitochondrial encephalopathy, lactic acidosis, stroke-like symptoms (MELAS) syndrome is a specific mitochondrial myopathy that results in defects in respiratory enzyme complexes I and IV.

This ultimately causes defects in aerobic metabolism, especially in high-energy-requiring organs, leading to an obvious concern with anesthetic management.

Mitochondrial disease (MD) is recognized as an important cause of a wide range of physiologic changes that affect the perioperative period [1], strongly affected by anesthetics.

We managed a 36-year male patient with MELAS, underwent a ureteroscopy, lithotripsy and indwelling double J stent exchange. The patient was successfully managed with a spinal/epidural anaesthesia.

Keywords: MELAS; Anesthetic Management; Myopathy; Genetics

References

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Citation

Citation: Refaat Shehab and MO Ababneh. “Anesthetic Management of a Patient with Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Symptoms (MELAS): A Case Report”. Acta Scientific Cancer Biology 5.10 (2021): 04-07.

Copyright

Copyright: © 2021 Refaat Shehab and MO Ababneh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.018

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