Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Mini Review Volume 5 Issue 9

Somatic Mutations and Cancer

Muhammad Saleem1, Munir Ahmed2, Aamir Ali Abro3 and Gang Chen1*

1College of Bioscience and Biotechnology, Yangzhou University, Jiangsu, China
2College of Food Science and Engineering, Yangzhou University, Jiangsu, China
3State Key Laboratory of Cotton, Biology Institute of Cotton Research Institute, Chinese Academy of Agriculture Sciences Anyang (CAAS), PR China

*Corresponding Author: Gang Chen, College of Bioscience and Biotechnology, Yangzhou University, Jiangsu, China.

Received: July 12, 2021; Published: August 19, 2021


Most of the mutations that accumulate in somatic cells throughout the life time of a person do not have any effects but some mutations can cause serious consequences like cancer (which after originating from a a single cell due to mutations in the genome starts to behave abnormally). There was a limited information of mutational processes and its consequences but recent advances in genome sequencing technologies due to unprecedented efforts has greatly revolutionized our understandings in this regard. In this review, I have briefly summarized about our current knowledge of the somatic mutations that that lead to cancer, its causes, possible ways which we are using for further studies and future premises.

Keywords: Somatic Mutations; Cancer; Aging; Genome; Repair Mechanism; Driver Mutations; Passenger Mutations; DNA Sequencing Technology


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Citation: Gang Chen., et al. “Somatic Mutations and Cancer". Acta Scientific Medical Sciences 5.9 (2021): 14-17.


Copyright: © 2021 Gang Chen., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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