Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Review Article Volume 5 Issue 2

Radiotherapy - A Focused Ray of Hope

Aklanta Kumar Gogoi1, Shivu ME2, Ravi Varma M3, Swati Pichika4 and Karthik D Yadav5*

1Department of Oral and Maxillofacial Surgery, India
2Reader, Department of Oral Medicine and Radiology, The Oxford Dental College, India
3Assistant Professor, Department of Orthodontics, Vishnu Dental College, India
4Assistant Professor, Department of Community, Vishnu Dental College, India
5Assistant Professor, Department of Oral Medicine and Radiology, KGF College of Dental Sciences, India

*Corresponding Author: Karthik D Yadav, Assistant Professor, Department of Oral Medicine and Radiology, KGF College of Dental Sciences, India.

Received: January 18, 2021; Published: January 30, 2020



  Oral carcinoma has occupied the sixth position with the 5 year survival rate at 50% or even less. Over the years various other diagnostic methods have been added for the process of diagnosis, however they are just adjunctive to the screening methods. Right treatment at the right time remains as a very important aspect even today and is considered to play a vital role in achieving a good prognosis. Treatment includes surgery, chemotherapy, radiotherapy and many more. However, the role of each of the treatment is to eradicate oral carcinoma but has its own side effects. Radiotherapy can be used as a single modality as well as an adjuvant to the surgical management after surgery. However, the side effects is a matter of concern in radiotherapy. Herein, this article focuses on radiotherapy and the pathways to deliver the same for a better life.

Keywords: Oral Carcinoma; Radiotherapy; Chemotherapy



  1. Messadi DV., et al. “The clinical effectiveness of reflectance optical spectroscopy for the in vivo diagnosis of oral lesions”. International Journal of Oral Science 6 (2014): 162-167.
  2. Fedele S. “Diagnostic aids in the screening of oral cancer”. Head and Neck Oncology 1 (2009): 5.
  3. Vashisht N., et al. “Chemiluminescence and Toluidine Blue as Diagnostic Tools for Detecting Early Stages of Oral Cancer: An in vivo Study”. JCDR - Journal of Clinical and Diagnostic Research 8 (2014): ZC35-ZC38.
  4. Vissink A and Jansma J. “Oral sequelae of head and neck Radiotherapy”. Critical Reviews in Oral Biology and Medicine 14 (2003): 199-208.
  5. Vissink A., et al. “Prevention and treatment of the consequences of Head and neck Radiotherapy”. Critical Reviews in Oral Biology and Medicine 14 (2003): 213-224.
  6. Bhide S A and CM Nutting. “Advances in radiotherapy for head and neck cancer”. Oral Oncology 46 (2010): 439-444.
  7. Baig M. “Current advances in radiotherapy of head and neck malignancies”. Journal of International Oral Health 5 (2013): 119-123.
  8. International commission on radiation units: Prescribing, recording and reporting photon beam therapy. Supplement to ICRU report 50. Bethseda. International commission on radiation Units and measurements, MD, ICRU (1999).
  9. Bhide S and Clark C. “Results of Intensity Modulated radiotherapy in laryngeal and hypopharyngeal cancer: a dose escalation study”. Radiotheroncology 82 (2007): S74-75.
  10. B Jorie and B Oak. “Intensity Modulated Radiation Therapy”. Radiological Society of North America (2014): 1-5.
  11. Parvathaneni U., et al. “Technical Advances and pitfalls in Head and Neck Radiotherapy”. Journal of Oncology (2012): 1-13.
  12. Okonogi N and Oike T. “Current advances in radiotherapy for newly diagnosed glioblastoma multiforme”. Journal of Neurology and Neurophysiology 5 (2014): 4.
  13. Jakel O and Schlagel W. “Radiation therapy with charged particles”. Seminars in Radiation Oncology (2016): 249-259.
  14. Pontus KE. “Radioimmunodetection and radioimmunotherapy of head and neck cancer”. Oral Oncology 40 (2004): 761-772.
  15. Suit H., et al. “Proton vs carbon ion beams in the definitive radiation treatment of cancer patients”. Radiotherapy Oncology 95 (2010): 3-22.
  16. Blakety E A. “Cell inactivation by heavy charged particles”. Radiation and Environmental Biophysics 31 (1992): 181-196.
  17. Castro J R and Saundero WM. “Treatment of cancer with heavy charged particles”. International Journal of Radiation Oncology, Biology, Physics 8 (1982): 2192-2198.
  18. Bajoria AA., et al. “Boron neutron capture therapy – redefining radiotherapy”. International Journal of Current Research 6 (2014): 8834-8838.
  19. Vanetti E. “Volumetric modulated arc radiotherapy for carcinomas of the oropharynx, hypopharynx and larynx: a treatment planning comparison with fixed field IMRT”. Radiotherapy and Oncology 92 (2009): 111-117.
  20. Verbakel W F. “Volumetric intensity modulated arc therapy vs conventional IMRT in head and neck cancer: a comparative planning n dosimetric study”. International Journal of Radiation Oncology, Biology, Physics 74 (2009): 252-259.
  21. Federick W and George W. “Current status and recent advances in radiotherapy of lung cancer”. Chest 71 (1977): 635-637.
  22. Gunderson LL., et al. “Current Clinical Oncology, Intraoperative Electron Beam Irradiation: Physics and Techniques”. 2nd ed. NY, USA: Humana Press (2011): 51-71.
  23. Calvo FA. Intraoperative radiation therapy. In: Perez CA, Brady LW, Halperin EC, eds. Principles and Practice of radiation Oncology. Boston, USA: Lippincott (2004): 428-456.


Citation: Karthik D Yadav., et al. “Radiotherapy - A Focused Ray of Hope". Acta Scientific Medical Sciences 5.2 (2021): 10-14.


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