Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Research Article Volume 5 Issue 1

Percutaneous Treatment of Degenerative Disc Disease with Radiopaque Gelified Ethanol (Discogel); Initial Experience in Iran

Mohammad Reza Babaei1*, Firoozeh Foroozand2, Masih Rikhtehgar3, Mohammad-Ali Mohammadi-Vajari3*, Ali Razmkon4, Hossein Ghanaati5, Hazhir Saberi6, Alireza Rasekhi7, Seyed Masoud Hashemi8, Majid Zohrabi9, Hamid Behtash10 and Jacques Théron11

1Assistant Professor of Interventional Radiology, Firozgar Hospital, Iran University of Medical Sciences, Tehran, Iran
2Medical Doctor at Emergency Department, Affiliated to Shahid Beheshti Medical University, Tehran, Iran
3Radiology Resident, Department of Radiology, Iran University of Medical Sciences, Tehran, Iran
4Assistant Professor of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran
5Professor of Radiology, Department of Radiology, Imam Khomeini Hospital, University of Medical
6Advanced Diagnostic and Interventional Radiology Research Center, Medical Imaging Center, Imam khomeini Hospital, Keshavarz Blvd., Tehran, Iran
7Department of Radiology, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
8Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences and Associated Professor, Department of Anesthesiology, Pain Clinic, Akhtar Hospital, Tehran, Iran
9Department of Neurosurgery, Nikan Hospital, Tehran, Iran
10Department of Orthopedic and Spinal Surgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
11Neuroradiologist and Interventional Radiologist, Ex Professor of Radiology at Caen University Hospital, Iran

*Corresponding Author: Mohammad Reza Babaei, Assistant Professor of Interventional Radiology, Firozgar Hospital, Iran University of Medical Sciences, Tehran, Iran and Mohammad-Ali Mohammadi-Vajari, Radiology Resident, Department of Radiology, Iran University of Medical Sciences, Tehran, Iran.

Received: March 18, 2020; Published: November 30, 2020

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Abstract

Background: Minimally-invasive treatments of degenerative disc disease are becoming more popular. Various intra-discal procedures have been introduced since many years ago, with variable outcome. Discogel has been recently introduced with promising results.

Purpose: To present our initial experience with intra-discal injection of Discogel in Iranian patients, to evaluate its efficacy and safety.

Material and Methods: 100 Patients with symptomatic lumbar or cervical disc herniation who failed conservative nonsurgical treatment, were included into the study. Discogel was injected under controlled fluoroscopic/CT scan guidance using standardized techniques. For patient evaluation, regular follow ups were carried out for assessing pain intensity on visual analog scale (VAS).

Results: The procedure lasted from 15 to 90 minutes depend on the number of levels that must be injected, and the whole admission took from 3 to 24 hours. Median VAS score was 10 before injection, which dropped to 5 at 1 week post-injection, and 0 at 1 month post- injection. Only 3 patient reported significant remaining pain at 1 months of follow- up that underwent operation intervention. No complications were noted.

Conclusion: This preliminary study shows efficacy and safety of Discogel intradiscal injection in selected cases. Further long-term follow-up is needed to evaluate the results.

Keywords: Discogel; Disc Herniation; Radiopaque Gelified Ethanol

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References

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  2. M Bellini., et al. “Percutaneous injection of Radiopaque Gelified Ethanol for the Treatment of Lumbar and Cervical Intervertebral Disk Herniations: Experience and Clinical Outcome in 80 Patients”. American Journal of Neuroradiology3 (2014): 600-605.
  3. Volpentesa G., et al. “Lumbar Percutaneous Injection of Radiopaque Gelified Ethanol (“Discogel”) in Patients with Low Back and Radicular Pain”. Journal of Pain and Relief 3 (2014): 145.
  4. T Sola., et al. “Herniated disk: treatment percutaneous using discogel”.
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  6. AD Kelekis, et al. “Quality assurance guidelines for percutaneous treatment of intervertebral discs”. CIRSE.
  7. L Saliba., et al. “Efficacite du discogel dans le tratement de la hernie discale” (2010).
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  10. Freemont AJ., et al. “Nerve in growth into diseased intervertebral disc in chronic back pain”. Lancet 350 (1997): 178-181.
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  12. S Marcia., et al. “Efficacy of Discogel radiopaque gelified ethanol+ etilcellulose in treatment of contained disc herniations: A preliminary experience”. Radiology.
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Citation

Citation: Mohammad Reza Babaei., et al. “Percutaneous Treatment of Degenerative Disc Disease with Radiopaque Gelified Ethanol (Discogel); Initial Experience in Iran”. Acta Scientific Cancer Biology 5.1 (2021): 14-17.




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