Acta Scientific Cancer Biology (ASCB)

Research Article Volume 4 Issue 12

Detection of Cervical Cytological Abnormalities by Pap Smear Method Among Women Attending the Screening Clinic of Nsambya Hospital

Mwesigwa Boaz1*, Andrew Livex Okwi2 and Othieno Emmanuel2

1Department of Cytology, Alzahra Specialty Hospital, Mogadishu, Somalia
2Department of Pathology, School of biomedical sciences, College of Health Sciences, Makerere University

*Corresponding Author: Mwesigwa Boaz, Department of Cytology, Alzahra Specialty Hospital, Mogadishu, Somalia.

Received: January 09, 2020; Published: November 30, 2020

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Abstract

Background: Cervical cancer is an important public health problem. In Uganda, it ranks the most frequent cause of cancer among women aged between 15 to 44 years of age. Early detection and eradication of cervical cancer and its precursor lesions is the mainstay for control of this disease. The Pap smear method is the most cost-effective means of screening cervical pre-malignant, malignant processes and non-neoplastic lesions. 

Aim: To describe the cervical cytological abnormalities as detected by Pap smear method and to determine the prevalence of such abnormalities

Methodology: This was a prospective study, in which a total of 175 women were recruited from May to June, 2016. Cervical samples were collected from these women and stained according to the papanicolaou staining protocol. Results were reported using the 2014 Bethesda reporting system. 

Results: Out of 175 cases, 163 (93.1%) were reported as negative for intraepithelial lesion or malignancy [NILM]. Cervical intraepithelial lesions were reported in 12 (6.9%) cases which included atypical squamous cells of undetermined significance [ASCUS] in 4(2.3%) cases, atypical squamous cells cannot exclude high grade squamous intraepithelial lesions [ASCH] in 1(0.6%) case, low-grade squamous intraepithelial lesion [LSIL] in 5 (2.9%) cases, high-grade squamous intraepithelial lesion [HSIL] in 1(0.6%) case and atypical glandular cells [AGC] in 1(0.6%) case. 

Conclusion: Cervical cytology by pap smear method should be used to screen women routinely because it is an effective method in detecting pre-malignant and malignant lesions of the cervix 

Keywords: Cervical Cancer; Cervical Intraepithelial Neoplasia; Human Papilloma Virus; Papanicolaou Smear

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References

  1. David JK and Alison N F “Towards Prevention of Cervical Cancer in Africa”. Report from Meeting at St. Catherine’s College, Oxford University (2009).
  2. Sankaranarayanan R and Ferlay J “Worldwide burden of gynaecological cancer: the size of the problem”. Best Practice and Research Clinical Obstetrics and Gynaecology 20.2 (2006): 207-225.
  3. World Health Organization. Strengthening Cervical Cancer Prevention and Control. Geneva, Switzerland: Report of the GAVI–UNFPA–WHO meeting (2009).
  4. Marluce Bibbo and David C Wilbur. Comprehensive cytopathology 3rd Edition (2008): 47.
  5. Pap smear: Medlineplus Lab Test Information (2018).
  6. Edmund S Cibas and Barbara S. “Ducatman. Cytology, Diagnostic Principles and Correlates (2009).
  7. MOPHS. National Cervical Cancer Prevention Programme”. Nairobi, Kenya (2012): 2.
  8. Okwi AL., et al. “Cervical cancer cases as seen by Papanicolaou method in selected districts of Uganda from 2004-2008”. Africa Journal of Animal and Biomedical Sciences 5.1 (2010): 65-69.
  9. Mbachu II and Umeononihu OS. “The role of Human papillomavirus (HPV) Testing in Cervical Cancer screening”. Afrimedic Journal 3.1 (2012).
  10. Hawa Inna. Prevalence of abnormal cervical smears and knowledge of cervical cancer screening among women attending gyaecology clinic of Hospital Minna, Nigeria (2014). 
  11. Avidime S., et al. “Pattern of cervical dysplasia among women of reproductive age in Zaria, Northern Nigeria”. Journal of Tropical Medicine 16 (2014): 52-55.
  12. Wanyoike-Gichuhi J., et al. “Prevalence of cervical cytology abnormalities among Hiv infected women at Rwanda Military Hospital”. East African Medical Journal 91.10 (2014): 333-340.
  13. Mulay K., et al. “A comparative study of cervical smears in an urban Hospital in India and a population-based screening program in Mauritius”. Indian Journal of Pathology and Microbiology 52.1 (2009): 34-37.
  14. Imai A., et al. “Trend of incidence in positive cervical smears from 2002-2010 in Ningen Dock, a special Japanese health check-up system”. Ningen Dock 26 (2012): 923-926.
  15. Misra JS., et al. “Risk factors associated with squamous intraepithelial lesions of cervix”. Journal of Cytology 19.2 (2002): 153-158.
  16. Castañeda-Iñiguez MS., et al. “Risk factors for cervico vaginal uterine cancer in Zecalecos”. Salid Publica Mex 40 330-338.
  17. Bhalla P., et al. “Prevalence of bacterial vaginosis among women in Delhi, India”. Indian Journal of Medical Research 125.2 (2007): 167-172.
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Citation

Citation: Mwesigwa Boaz.,et al. “Detection of Cervical Cytological Abnormalities by Pap Smear Method Among Women Attending the Screening Clinic of Nsambya Hospital”.Acta Scientific Cancer Biology 4.12 (2020): 28-31.




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