Jaypee Hospital, India
*Corresponding Author: Ruchir Tandon, Jaypee Hospital, India.
Received: May 08, 2018; Published: May 28, 2018
Citation: Ruchir Tandon. “Targeted Therapies in EGFR and ALK Wild Type Advanced NSCLC in an Elderly Patient". Acta Scientific Cancer Biology 2.5 (2018).
Adenocarcinoma variants of NSCLC often present without an activating EGFR mutation or ALK translocation. In unresectable stage III Guidelines recommend definitive concurrent chemoradiotherapy or induction chemotherapy with platinum-based doublet chemotherapy followed by Radiotherapy. Patient’s performance status, age, issues of toxicity, convenience and acceptability should be seen while selecting the appropriate therapy for an individual patient. EGFR TKIs show promising results even in EGFR wild type cases.
Keywords: Adenocarcinoma (NSCLC); EGFR Wild Type; Afatinib
Copyright: © 2018 Ruchir Tandon. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.