Yogitha Bala Dugyala and Shanthi Kumari Kuthadi*

Department of Microbiology, Osmania University, Hyderabad, India

*Corresponding Author: Shanthi Kumari Kuthadi, Department of Microbiology, Osmania University, Hyderabad, India.

Received: April 15, 2024; Published: April 30, 2024

Abstract

The present study demonstrates the antibacterial activity of marine bacteria isolated from Velankanni Beach, Chennai, India. Five distinct isolates were identified, with Micrococcus luteus (YSD1) exhibiting the most promising antibacterial properties. The crude compounds extracted from YSD1 were examined for their antibacterial activity using the agar-well diffusion method against Proteus mirabilis ATCC 25933, Bacillus subtilis ATCC, Bacillus cereus ATCC, and methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300. Gas chromatography-mass spectrometry (GC-MS) analysis revealed 2-pentanone at high intensity, with potential applications in cancer treatment. This research underscores the potential of marine ecosystems as a source of novel antibiotics and the significance of reliable approaches in pharmaceutical discovery. Further research is required to corroborate these findings against a wider range of pathogens and to explore their ameliorative potential and mechanisms of action. The results of this study contribute to the wider field of research by spotlighting the untapped potential of marine ecosystems in bringing novel antibiotics to light, thereby paving the way for future studies to combat antibiotic resistance.

Keywords: Marine; Antibacterial Activity; Micrococcus luteus; Agar Diffusion Method; Thin-layer Chromatography (TLC); Gas Chromatography-Mass Spectrometry (GC-MS) Analysis; 2-Pentanone

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Citation

Citation: Yogitha Bala Dugyala and Shanthi Kumari Kuthadi. “Antibacterial Activity of Micrococcus luteus YSD1 Isolated from Velankanni Water Source, Tamil Nadu".Acta Scientific Biotechnology 5.2 (2024): 26-33.

Copyright

Copyright: © 2024 Yogitha Bala Dugyala and Shanthi Kumari Kuthadi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.