Sristi Dasgupta* and Disha Nayak
Vellore Institute of Technology, India
*Corresponding Author:Sristi Dasgupta, Vellore Institute of Technology, India.
Received: November 29, 2023; Published: December 08, 2023
Lung carcinoma stands as the preeminent contributor to cancer-related fatalities on a global scale. From the inception of the 20th century, a myriad of infectious entities linked to pulmonary malignancy has come to light. Elucidating mechanisms encompassing systemic inflammatory pathways, arising as a consequence of microbial persistence within the pulmonary milieu, emerges as a pivotal determinant in propelling the trajectory of lung carcinogenesis. The chronic inflammation entwined with infections instigating lung cancer is acknowledged to precede the genesis of tumors, exercising a formidable influence on therapeutic responses. Emanating from both viral and bacterial origins, infections orchestrate the activation of inflammatory cells and pathways, thereby orchestrating a complex interplay within the landscape of lung cancer development. Within the confines of this review, an expansive survey of recent scholarly investigations is undertaken, delving into the intricate associations between viral and bacterial pathogens and lung carcinoma. Special emphasis is placed on delineating the disruptive potential of infectious organisms throughout the spectrum of oncogenic processes, permeating the very fabric of immunity. Furthermore, a nuanced exploration unfolds, navigating the intricate interdependence between the evolution of lung tumors and the orchestration of inflammatory cascades.
Keywords: Lung Carcinoma; Global Scale; Lung Cancer
Citation: Sristi Dasgupta and Disha Nayak. “Cancer's Covert Culprits: Unraveling the Intricate Interplay Between Pathogens and the Oncogenic Landscape".Acta Scientific Biotechnology 4.5 (2023): 34-40.
Copyright: © 2023 Sristi Dasgupta and Disha Nayak. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.