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Abstract

  HIV is a virus that effects the immune system of the body which in turn increases the risk of attaining an infection and diseases. It has no cure till now however some treatment can help like antiretroviral drugs and an individual can lead a normal life not a healthy reproductive life. However, there are some cells which have a mutation CCR5-delta 32 which are immune to HIV virus. It was found in the bone marrow of a donor which was then transplanted in a patient known as “Berlin patient”. These cells show a great potential of curing HIV but still there are some rare cases in which the individual were infected by HIV virus although they had two copies of CCR5 mutant cells form each of patients. So, researchers used CRISPR technology to gene edit normal cells into CCR5 mutant cells and inserted in the patient body to cure HIV.

Keywords: CRISPR Technology; HIV; CCR5 Mutant Cells; CCR5-Delta 32

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References

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Citation

Citation: Kartik Pal. “CRISPR Technology: A Potential Cure for HIV". Acta Scientific Biotechnology 1.10 (2020): 18-23.

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Copyright

Copyright: © 2020 Kartik Pal. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.