Pseudomonas aeruginosa is a gram-negative infectious agent to human remains associated with several diseases including urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections. The antibiotics use lead to control of bacterium growth and disease effectively. Recent studies have shown that new cases of Pseudomonas aeruginosa infections with higher frequency are reported worldwide. The growing concern worldwide is acquired drug resistance in Pseudomonas aeruginosa and the prevalence of such drug-resistant pathogens in intensive care units. The entire microbial world is evolved with unique genome plasticity and capacity to acquire additional gene/s as per need, including the drug resistance gene. It is now evident that extensive use of antibiotics and antimicrobial agents for a longer duration of time stimulated such pathogens for adaptation. The antibiotic pressure is selection criteria in microbial communities to alter genome by acquiring foreign DNA and or mutation in the genome itself. The entire microbial world is unique in having effective and robust enzyme/s capable of degradation of antibiotics and antimicrobial agents. Such capacity allows microbes to grow in hearse conditions as well. This is one of the possible mechanisms behind the rise of new cases of Pseudomonas aeruginosa in Intensive Care Units.

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Citation

Citation: Mahendra Kumar Verma. “Rise in Drug-Resistant Pseudomonas aeruginosa Infections in Intensive Care Units". Acta Scientific Biotechnology 1.9 (2020): 01-02.

Copyright

Copyright: © 2020 Mahendra Kumar Verma. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.