Kajal Patel*, Prasanna K Pradhan, Ritu Sapra and Dhananjay Meshram
Department of Quality Assurance, Pioneer Pharmacy Degree College, Sayajipura, Vadodara, Gujarat, India
*Corresponding Author: Kajal Patel, Department of Quality Assurance, Pioneer Pharmacy Degree College, Sayajipura, Vadodara, Gujarat, India.
Received: February 25, 2020; Published: March 16, 2020
Hypertension is the most common regulating risk factor for cardiovascular disease (CVD) and death; the increased risk associated with blood pressure (BP) elevation can be greatly reduced by treatment with antihypertensive drugs that lower both BP and related target organ damage. Azelnidipine has also been confirmed to have cardio-protective, neuroprotective, and anti-atherosclerotic properties, and has also been found to prevent insulin resistance. Azelnidipine is dihydropyridine derivative with calcium antagonistic activity. Azelnidipine is inhibits trans membrane Ca+2 influx through the voltage dependent channels of smooth muscle in vascular walls. They enter the cells through cell membrane and is used for treatment of essential hypertension and angina pectoris. This review covers most recent analytical methods such as various spectroscopic methods, chromatographic methods and other methods for determination of Azelnidipine in various pharmaceutical dosage forms and biological matrix were reported.
Keywords: Azelnidipine; Analytical Methods; Antihypertensive Drug; Matrices; Estimation
Citation: Kajal Patel. “In Depth Investigation of Analytical Methods for the Determination of Azelnidipine in Biological Fluid and Pharmaceutical Dosage Forms: A Review". Acta Scientific Biotechnology 1.4 (2020): 13-17.
Copyright: © 2020 Kajal Patel. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.