Abstract

  Mitophagy is referred as a process in which removal of dysfunctional mitochondria takes place by autophagy. Mitochondria contains some proteins which helps in achieving this process that are PINK1, PARKIN, NIPSNAP 1, NIPSNAP 2. However, NIPSNAP 1 and NIPSNAP were discovered after initially it was assumed that only PINK1 and PARKIN proteins are only responsible for mitophagy but now it is cleared after series of experiments. Mitophagy is a crucial event in terms of health of a living cell because it ensures proper cellular functions. Here we will focus on pathway which a mitochondrion goes under to achieve mitophagy and we will also see how mitophagy is important for an organism.

Keywords: Mitophagy; Mitochondria; Organism

References

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Citation

Citation: Sarika Chaturvedi and Kartik Pal. “Mitophagy and its Importance".Acta Scientific Biotechnology 1.1 (2020): 15-17.

Copyright

Copyright: © 2020 Sarika Chaturvedi and Kartik Pal. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.