Acta Scientific Biotechnology (ASBT)

Review Article Volume 1 Issue 1

Association of ACE Gene with Human Performance

Nayyer Naqvi1, Naureen Naeem1*, M Amjad Khan2, Ayesha Kanwal1 and Sana Shahbaz1

1Department of Biology, Lahore Garrison University, Pakistan
2Department of Chemistry, Lahore Garrison University, Pakistan

*Corresponding Author:Naureen Naeem, Department of Biology, Lahore Garrison University, Pakistan.

Received: December 09, 2019; Published: December 30, 2019



  The ACE gene provides instructions for making the angiotensin-converting enzyme. The aim of this project is to check the association of ACE gene with human performance. The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II causes blood vessels to narrow (constrict), which results in increased blood pressure. This protein also increases the production of the hormone aldosterone levels, which triggers the absorption of water and salts by the kidneys. ACE is a zinc metalloenzyme. The zinc ion is essential to its activity, since it directly participates in the catalysis of the peptide hydrolysis. Therefore, ACE can be inhibied by metal-chelating agents.

Keywords: ACE Gene; Enzyme; Kidney



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Citation: Naureen Naeem., et al. “Association of ACE Gene with Human Performance".Acta Scientific Biotechnology 1.1 (2020): 11-14.


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