Abstract

  The ACE gene provides instructions for making the angiotensin-converting enzyme. The aim of this project is to check the association of ACE gene with human performance. The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II causes blood vessels to narrow (constrict), which results in increased blood pressure. This protein also increases the production of the hormone aldosterone levels, which triggers the absorption of water and salts by the kidneys. ACE is a zinc metalloenzyme. The zinc ion is essential to its activity, since it directly participates in the catalysis of the peptide hydrolysis. Therefore, ACE can be inhibied by metal-chelating agents.

Keywords: ACE Gene; Enzyme; Kidney

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Citation

Citation: Naureen Naeem., et al. “Association of ACE Gene with Human Performance".Acta Scientific Biotechnology 1.1 (2020): 11-14.

Copyright

Copyright: © 2020 Naureen Naeem., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.