Acta Scientific ANATOMY

Editorial Volume 2 Issue 6

Plenary and Malevolent-Myoepithelial Carcinoma Salivary Gland

Anubha Bajaj*

Consultant, Histopathologist, A.B., Diagnostics, India

*Corresponding Author: Anubha Bajaj, Consultant, Histopathologist, A.B., Diagnostics, India.

Received: September 01, 2023; Published: September 15, 2023


Myoepithelial carcinoma of salivary gland emerges as a malignant neoplasm singularly constituted of myoepithelial cells which demonstrates an infiltrative pattern of tumour evolution. Myoepithelial carcinoma of salivary gland may arise de novo or as myoepithelial carcinoma ex pleomorphic adenoma. PLAG1 genetic fusion is encountered in >50% neoplasms. The alterative terminology of malignant myoepithelioma is not recommended. Currently, an acceptable, well defined tumour grading system is absent. Myoepithelial carcinoma configures around 4% of salivary gland neoplasms. Nevertheless, tumour frequency may be underrated as myoepithelial carcinoma can be underdiagnosed. Myoepithelial carcinoma may incriminate paediatric subjects.


  1. Argyris PP and Wakely PE Jr. “Cytopathology of salivary gland myoepithelial carcinoma: A study of 13 cases and review of the literature”. Journal of the American Society of Cytopathology (2023): S2213-2945.
  2. Syrnioti G., et al. “Myoepithelial Carcinoma Ex Pleomorphic Adenoma of the Submandibular Gland: A Case Report”. Cureus3 (2023): e35722.
  3. Skálová A., et al. “Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands”. Head and Neck Pathology 1 (2022): 40-53.
  4. Gontarz M., et al. “Myoepithelial Carcinoma Arising in a Salivary Duct Cyst of the Parotid Gland: Case Presentation”. Medicina (Kaunas)2 (2023): 184.
  5. Luo Y. “Myoepithelial carcinoma of major salivary glands: Analysis of population-based clinicopathologic and prognostic features”. Translational Oncology 20 (2022): 101410.
  6. Lavareze L., et al. “Clinicopathological and survival profile of patients with salivary gland myoepithelial carcinoma: A systematic review”. Journal of Oral Pathology and Medicine 2 (2023): 101-108.
  7. Image 1 Courtesy: Springer link.
  8. Image 2 Courtesy: Medscape reference.


Citation: Anubha Bajaj. “Plenary and Malevolent-Myoepithelial Carcinoma Salivary Gland".Acta Scientific Anatomy 2.6 (2023): 01-03.


Copyright: © 2023 Anubha Bajaj. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

News and Events

Contact US