Acta Scientific Women's Health (ASWH)

Review Article Volume 6 Issue 5

An Uncommon Case Report of Mauric Syndrome or Diabetic Glycogenosis in Girl

Rahul Hajare*

Department of Women’s Health, India

*Corresponding Author: Rahul Hajare, Department of Women’s Health, India

Received: April 10, 2024; Published: April 18, 2024

Abstract

Mauriac syndrome is an uncommon side effect of poorly controlled adolescent diabetes mellitus. We present the case of a 17-year-old patient with type 1 diabetes who was admitted to the hospital because of a serious hyper glycemic imbalance. A failure to thrive and hepatomegaly were noted during the clinical assessment. Biological investigations revealed anicteric cholestasis, severe cytolysis, and hyperglycemia. The foundation of the care was provided by insulin and hydration therapies. The etiological examination for liver dysfunction produced negative results. Biology and medicine have positively evolved. The diagnosis of hepatic glycogenesis was upheld in light of several anamnestic and clinical evidences, as well as the absence of further abnormalities linked to hepatic disorders. The outcome was elevated blood sugar. Blood transaminases were also increased. An abdominal ultrasound indicated homogeneous hepatomegaly. Viral hepatitis serology and immunological testing came back negative, and a liver biopsy confirmed the hepatocyte ballooning. Given the favorable outcomes observed during high-dose insulin treatment, the diagnosis of Mauriac syndrome was retained.

Keywords: Mauriac Syndrome; Hepatic Glycogenosis; Diabetes Mellitus; Failure to Thrive; Hepatomegaly

References

  1. Mauriac P. “Gros ventre, hepatomegalie, troubles de las croissance chez les enfants diabetiques traits depuisplusieursannes par l’insuline”. GaxHebd Med Bordeaux 26 (1930): 402-410.
  2. Haller MJ., et al. “Type 1 diabetes in the child and adolescent”. In: Pediatric endocrinology. CRC Press (2006): 89-108.
  3. Gutch M., et al. “Re-emergence of a rare syndrome: a case of mauriac syndrome”. Indian Journal of Endocrinology Metabolism 17 (2013): S283.
  4. Nordlie RC., et al. “Regulation of glucose production by the liver”. Annual Review of Nutrition1 (1999): 379-406.
  5. Bua J., et al. “Hepatic glycogenosis in an adolescent with diabetes”. Journal of Pediatrics 6 (2010): 1042.
  6. Ruschhaupt DG and Rennert OM. “Recurrent hepatomegaly and transient alteration of liver functions in an adolescent with diabetic acidosis”. Clinical Pediatrics2 (1970): 122-124.
  7. Munns CFJ., et al. “Hepatic glycogenosis: reversible hepatomegaly in type 1 diabetes”. Journal of Paediatric Child Health5 (2000): 449-452.
  8. Manderson WG., et al. “Liver glycogen accumulation in unstable diabetes”. Diabetes1 (1968): 13-16.
  9. Abaci A., et al. “Hepatic glycogenosis: a rare cause of hepatomegaly in Type 1 diabetes mellitus”. Journal of Diabetes and Its Complications 5 (2008): 325-328.
  10. Morrison EY and McKenzie K. “The Mauriac syndrome”. W Indian Medical Journal3 (1989): 180-182.
  11. Brouwers MC., et al. “Elevated lactate levels in patients with poorly regulated type 1 diabetes and glycogenic hepatopathy: a new feature of Mauriac syndrome”. Diabetes Care2 (2015): e11-12.

Citation

Citation: Svetlana Dubrovina. “Postoperative Hormonal Therapy - An Effective Way to Decrease the Risk of Endometriosis Recurrence"Acta Scientific Women's Health 6.5 (2024): 16-17.

Copyright

Copyright: © 2024 Svetlana Dubrovina. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.278

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is November 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US