Talha Paracha*

Sr Embryologist, Associate Member Royal College of Pathology, UK, Life, IVF Multan, Meher Plaza Nishtar Road Multsn, Punjab, Pakistan

*Corresponding Author: Talha Paracha, Sr Embryologist, Associate Member Royal College of Pathology, UK, Life, IVF Multan, Meher Plaza Nishtar Road Multsn, Punjab, Pakistan.

Received: February 02, 2024; Published: February 28, 2024

Abstract

An infertile couple seeking fertility treatment from LIFE IVF Multan, Pakistan, where male was diagnosed with HCV positive and NOA. Female partner had her Fallopian tubes blocked while rest of the parameters were in normal ranges .Couple was advised for Testicular Biopsy and to undergo ICSI cycle .Only hindrance was blood contaminating testicular tissue with viral particles so an modified washing technique was adopted mentioned elsewhere(2), claiming to reduce viral load in biopsied sample which was followed by vitrification of sample to further use in ICSI cycle .On day of procedure biopsied sample was thawed and observed for sperm motility which on absence was subjected to chemical activation .Couple was briefly informed on possible adverse outcomes low fertilization, Poor quality embryo, risk of cross infection and lack of adequate data on methodology adopted. The methodology adapted resulted in successful pregnancy, Mother was investigated for Anti HCV Abs on 1st trimester and after successful delivery of healthy baby ,both mother and infant was investigated again for Anti HCV Abs and both were found negative .This gives a preliminary proof for safety of the procedure adopted.

Keywords: Pregnancy; ICSI; TESE; Serodiscordant; HCV; Sperms

References

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2. Marianne Leruez-Ville., et al. “Intracytoplasmic sperm injection with micro surgically retrieved spermatozoa in a zoo spermic men infected with human immunodeficiency virus 1 or hepatitis c virus: the EP43 AZONECO ANRS study”. Journal of Fertility and Sterility 3 (2013): 713-717.
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Citation

Citation: Talha Paracha. “Successful Pregnancy After ICSI with TESE Sample in Serodiscordant Couple with Male Partner Sero Positive for HCV After Utilizing Modified Washing and Chemical Activation of Sperms Simultaneously"Acta Scientific Women's Health 6.3 (2024): 31-32.

Copyright

Copyright: © 2024 Talha Paracha. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.